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Andrew M Paluch

Explore the profile of Andrew M Paluch including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 183
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Recent Articles
1.
Brown N, Paluch A, Nashu M, Komurov K, Waltz S
Neoplasia . 2018 Aug; 20(9):917-929. PMID: 30121008
Current treatment strategies provide minimal results for patients with castration-resistant prostate cancer (CRPC). Attempts to target the androgen receptor have shown promise, but resistance ultimately develops, often due to androgen...
2.
Stuart W, Brown N, Paluch A, Waltz S
Am J Physiol Endocrinol Metab . 2015 Feb; 308(7):E562-72. PMID: 25648832
The Ron receptor tyrosine kinase is a heterodimeric, membrane-spanning glycoprotein that participates in divergent processes, including proliferation, motility, and modulation of inflammatory responses. We observed male C57BL/6 mice with a...
3.
Cai Y, Balli D, Ustiyan V, Fulford L, Hiller A, Misetic V, et al.
J Biol Chem . 2013 Jun; 288(31):22527-41. PMID: 23775078
The treatment of advanced prostate cancer (PCa) remains a challenge. Identification of new molecular mechanisms that regulate PCa initiation and progression would provide targets for the development of new cancer...
4.
Gray J, Paluch A, Stuart W, Waltz S
Cancer Lett . 2011 Oct; 314(1):92-101. PMID: 22004727
Previous studies have shown that the Ron receptor is overexpressed in prostate cancer and Ron expression increases with disease severity in humans and the mouse TRAMP model. Here, the causal...
5.
McFarland-Mancini M, Funk H, Paluch A, Zhou M, Giridhar P, Mercer C, et al.
J Immunol . 2010 May; 184(12):7219-28. PMID: 20483735
IL-6 modulates immune responses and is essential for timely wound healing. As the functions mediated by IL-6 require binding to its specific receptor, IL-6Ralpha, it was expected that mice lacking...