Premkumar Vummidi Giridhar
Overview
Explore the profile of Premkumar Vummidi Giridhar including associated specialties, affiliations and a list of published articles.
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8
Citations
327
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Recent Articles
1.
Giridhar P, Williams K, VonHandorf A, Deford P, Kasper S
Cancer Res
. 2019 Jan;
79(6):1124-1137.
PMID: 30626627
Prostate cancer stem cells (CSC) are implicated in tumor initiation, cancer progression, metastasis, and the development of therapeutic-resistant disease. It is well known that the bulk of prostate cancer cells...
2.
Giridhar P, Bell S, Sridharan A, Rajavelu P, Kitzmiller J, Na C, et al.
J Immunol
. 2016 Nov;
197(11):4228-4239.
PMID: 27794000
KIF3A, the gene encoding kinesin family member 3A, is a susceptibility gene locus associated with asthma; however, mechanisms by which KIF3A might influence the pathogenesis of the disorder are unknown....
3.
Zhou J, Giridhar P, Kasper S, Papautsky I
Biomicrofluidics
. 2014 Nov;
8(4):044112.
PMID: 25379097
Cell filtration is a critical step in sample preparation in many bioapplications. Herein, we report on a simple, filter-free, microfluidic platform based on hydrodynamic inertial migration. Our approach builds on...
4.
Williams K, Motiani K, Giridhar P, Kasper S
Exp Biol Med (Maywood)
. 2013 Apr;
238(3):324-38.
PMID: 23598979
The stem cell niche provides a regulatory microenvironment for cells as diverse as totipotent embryonic stem cells to cancer stem cells (CSCs) which exhibit stem cell-like characteristics and have the...
5.
Zhou J, Giridhar P, Kasper S, Papautsky I
Lab Chip
. 2013 Mar;
13(10):1919-29.
PMID: 23529341
Inertial microfluidics has been attracting considerable interest in recent years due to immensely promising applications in cell separations and sorting. Despite the intense attention, the moderate efficiencies and low purity...
6.
Williams K, Ghosh R, Giridhar P, Gu G, Case T, Belcher S, et al.
Cancer Res
. 2012 Aug;
72(20):5407-17.
PMID: 22915755
The oncoprotein stathmin 1 (STMN1) is upregulated in most, if not all, cancers of epithelial cell origin; therefore STMN1 is considered a target for cancer therapy. However, its role during...
7.
Giridhar P, Funk H, Gallo C, Porollo A, Mercer C, Plas D, et al.
Clin Exp Metastasis
. 2011 Sep;
28(8):887-97.
PMID: 21887537
One of the earliest metastatic events in human ovarian cancer, tumor spread to the omentum, may be influenced by expression of interleukin 6 (IL6) and its cognate receptor (IL6Rα). Previous...
8.
McFarland-Mancini M, Funk H, Paluch A, Zhou M, Giridhar P, Mercer C, et al.
J Immunol
. 2010 May;
184(12):7219-28.
PMID: 20483735
IL-6 modulates immune responses and is essential for timely wound healing. As the functions mediated by IL-6 require binding to its specific receptor, IL-6Ralpha, it was expected that mice lacking...