Andrew M Hemmings
Overview
Explore the profile of Andrew M Hemmings including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
48
Citations
826
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dudey A, Hughes G, Rigby J, Monaco S, Stephenson G, Storr T, et al.
ACS Omega
. 2025 Feb;
10(6):5963-5972.
PMID: 39989805
Indole-3-carbinol (I3C) is a metabolic derivative of glucobrassicin found in cruciferous vegetables. Known for its anticarcinogenic properties, I3C has been shown to target the NEDD4 family HECT E3 ligases, NEDD4-1...
2.
Zhou R, Liu Z, Wu T, Pan X, Li T, Miao K, et al.
Cell Commun Signal
. 2024 Dec;
22(1):585.
PMID: 39639305
Background: Epidermal growth factor receptor (EGFR) T790M mutation often occurs during long durational erlotinib treatment of non-small cell lung cancer (NSCLC) patients, leading to drug resistance and disease progression. Identification...
3.
Dudey A, Rigby J, Hughes G, Stephenson G, Storr T, Chantry A, et al.
J Enzyme Inhib Med Chem
. 2024 Sep;
39(1):2394895.
PMID: 39223706
The HECT E3 ubiquitin ligases 1 (WWP1) and 2 (WWP2) are responsible for the ubiquitin-mediated degradation of key tumour suppressor proteins and are dysregulated in various cancers and diseases. Here...
4.
Sharma Y, Hemmings A, Hemmings A, Deshmukh R, Pareek A
J Exp Bot
. 2024 Jun;
76(5):1370-1389.
PMID: 38847578
The rhizosphere contains both essential nutrients and potentially harmful substances for plant growth. Plants, as sessile organisms, must efficiently absorb the necessary nutrients while actively avoiding the uptake of toxic...
5.
Whitfield H, Rodriguez R, Shipton M, Li A, Riley A, Potter B, et al.
Biochemistry
. 2023 Dec;
63(1):42-52.
PMID: 38146842
Inositol phosphates and their pyrophosphorylated derivatives are responsive to the phosphate supply and are agents of phosphate homeostasis and other aspects of physiology. It seems likely that the enzymes that...
6.
Whitfield H, He S, Gu Y, Sprigg C, Kuo H, Chiou T, et al.
Biochem J
. 2023 Mar;
480(6):433-453.
PMID: 36896917
Myo-inositol tris/tetrakisphosphate kinases (ITPKs) catalyze diverse phosphotransfer reactions with myo-inositol phosphate and myo-inositol pyrophosphate substrates. However, the lack of structures of nucleotide-coordinated plant ITPKs thwarts a rational understanding of phosphotransfer...
7.
Rix G, Sprigg C, Whitfield H, Hemmings A, Todd J, Brearley C
PLoS One
. 2022 Aug;
17(8):e0272015.
PMID: 36044476
Phylogenetic analysis, homology modelling and biochemical methods have been employed to characterize a phytase from a Gram-negative soil bacterium. Acinetobacter sp. AC1-2 phytase belongs to clade 2 of the histidine...
8.
Acquistapace I, Thompson E, Kuhn I, Bedford M, Brearley C, Hemmings A
Int J Mol Sci
. 2022 Jun;
23(11).
PMID: 35683026
AppA, the periplasmic phytase of clade 2 of the histidine phosphatase (HP2) family, has been well-characterized and successfully engineered for use as an animal feed supplement. AppA is a 1D-6-phytase...
9.
Faba-Rodriguez R, Gu Y, Salmon M, Dionisio G, Brinch-Pedersen H, Brearley C, et al.
Plant Commun
. 2022 May;
3(2):100305.
PMID: 35529950
Grain phytate, a mixed metal ion salt of inositol hexakisphosphate, accounts for 60%-80% of stored phosphorus in plants and is a potent antinutrient of non-ruminant animals including humans. Through neofunctionalization...
10.
Bradley J, Fair J, Hemmings A, Le Brun N
Microbiology (Reading)
. 2021 Nov;
167(11).
PMID: 34825885
Ferritins are proteins forming 24meric rhombic dodecahedral cages that play a key role in iron storage and detoxification in all cell types. Their function requires the transport of Fe from...