Kristen R Maynard
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Explore the profile of Kristen R Maynard including associated specialties, affiliations and a list of published articles.
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45
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981
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Recent Articles
1.
Ramnauth A, Tippani M, Divecha H, Papariello A, Miller R, Nelson E, et al.
Cell Rep
. 2025 Feb;
44(2):115300.
PMID: 40009515
The dentate gyrus of the hippocampus is important for many cognitive functions, including learning, memory, and mood. Here, we present transcriptome-wide spatial gene expression maps of the human dentate gyrus...
2.
Bonev B, Castelo-Branco G, Chen F, Codeluppi S, Corces M, Fan J, et al.
Nat Neurosci
. 2024 Dec;
28(1):216.
PMID: 39681663
No abstract available.
3.
Bonev B, Castelo-Branco G, Chen F, Codeluppi S, Corces M, Fan J, et al.
Nat Neurosci
. 2024 Dec;
27(12):2292-2309.
PMID: 39627587
Over the past decade, single-cell genomics technologies have allowed scalable profiling of cell-type-specific features, which has substantially increased our ability to study cellular diversity and transcriptional programs in heterogeneous tissues....
4.
Gonzalez-Padilla D, Eagles N, Cano M, Pertea G, Jaffe A, Maynard K, et al.
bioRxiv
. 2024 Nov;
PMID: 39574597
Maternal smoking during pregnancy (MSDP) is associated with significant cognitive and behavioral effects on offspring. While neurodevelopmental outcomes have been studied for prenatal exposure to nicotine, the main psychoactive component...
5.
Kwon S, Parthiban S, Tippani M, Divecha H, Eagles N, Lobana J, et al.
GEN Biotechnol
. 2024 Sep;
2(5):399-417.
PMID: 39329069
Neuropathological lesions in the brains of individuals affected with neurodegenerative disorders are hypothesized to trigger molecular and cellular processes that disturb homeostasis of local microenvironments. Here, we applied the 10x...
6.
Brida K, Jorgensen E, Phillips R, Newman C, Tuscher J, Morring E, et al.
bioRxiv
. 2024 Jul;
PMID: 38948801
Drugs of abuse activate defined neuronal ensembles in brain reward structures such as the nucleus accumbens (NAc), which are thought to promote the enduring synaptic, circuit, and behavioral consequences of...
7.
Huuki-Myers L, Spangler A, Eagles N, Montgomery K, Kwon S, Guo B, et al.
Science
. 2024 May;
384(6698):eadh1938.
PMID: 38781370
The molecular organization of the human neocortex historically has been studied in the context of its histological layers. However, emerging spatial transcriptomic technologies have enabled unbiased identification of transcriptionally defined...
8.
Thompson J, Nelson E, Tippani M, Ramnauth A, Divecha H, Miller R, et al.
bioRxiv
. 2024 May;
PMID: 38712198
The hippocampus contains many unique cell types, which serve the structure's specialized functions, including learning, memory and cognition. These cells have distinct spatial organization, morphology, physiology, and connectivity, highlighting the...
9.
Maden S, Huuki-Myers L, Kwon S, Collado-Torres L, Maynard K, Hicks S
bioRxiv
. 2024 Apr;
PMID: 38617294
Relative cell type fraction estimates in bulk RNA-sequencing data are important to control for cell composition differences across heterogenous tissue samples. Current computational tools estimate relative RNA abundances rather than...
10.
Tippani M, Divecha H, Catallini 2nd J, Kwon S, Weber L, Spangler A, et al.
Biol Imaging
. 2024 Mar;
3:e23.
PMID: 38510173
Spatially resolved transcriptomics (SRT) is a growing field that links gene expression to anatomical context. SRT approaches that use next-generation sequencing (NGS) combine RNA sequencing with histological or fluorescent imaging...