Andreas Merdes
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Explore the profile of Andreas Merdes including associated specialties, affiliations and a list of published articles.
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45
Citations
2679
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Recent Articles
11.
Espigat-Georger A, Dyachuk V, Chemin C, Emorine L, Merdes A
J Cell Sci
. 2016 Nov;
129(22):4227-4237.
PMID: 27802164
Myotubes are syncytial cells generated by fusion of myoblasts. Among the numerous nuclei in myotubes of skeletal muscle fibres, the majority are equidistantly positioned at the periphery, except for clusters...
12.
Farache D, Jauneau A, Chemin C, Chartrain M, Remy M, Merdes A, et al.
J Biol Chem
. 2016 Sep;
291(44):23112-23125.
PMID: 27660388
Microtubules are nucleated from multiprotein complexes containing γ-tubulin and associated γ-tubulin complex proteins (GCPs). Small complexes (γTuSCs) comprise two molecules of γ-tubulin bound to the C-terminal domains of GCP2 and...
13.
Sana T, Baumann C, Merdes A, Soscia C, Rattei T, Hachani A, et al.
mBio
. 2015 Jun;
6(3):e00712.
PMID: 26037124
Unlabelled: Invasion of nonphagocytic cells through rearrangement of the actin cytoskeleton is a common immune evasion mechanism used by most intracellular bacteria. However, some pathogens modulate host microtubules as well...
14.
Scheidecker S, Etard C, Haren L, Stoetzel C, Hull S, Arno G, et al.
Am J Hum Genet
. 2015 Mar;
96(4):666-74.
PMID: 25817018
We have identified TUBGCP4 variants in individuals with autosomal-recessive microcephaly and chorioretinopathy. Whole-exome sequencing performed on one family with two affected siblings and independently on another family with one affected...
15.
Bouissou A, Verollet C, de Forges H, Haren L, Bellaiche Y, Perez F, et al.
EMBO J
. 2014 Jan;
33(2):114-28.
PMID: 24421324
γ-Tubulin is critical for microtubule (MT) assembly and organization. In metazoa, this protein acts in multiprotein complexes called γ-Tubulin Ring Complexes (γ-TuRCs). While the subunits that constitute γ-Tubulin Small Complexes...
16.
Villumsen B, Danielsen J, Povlsen L, Sylvestersen K, Merdes A, Beli P, et al.
EMBO J
. 2013 Oct;
32(23):3029-40.
PMID: 24121310
Centriolar satellites are small, granular structures that cluster around centrosomes, but whose biological function and regulation are poorly understood. We show that centriolar satellites undergo striking reorganization in response to...
17.
Cala O, Remy M, Guillet V, Merdes A, Mourey L, Milon A, et al.
PLoS One
. 2013 May;
8(5):e63908.
PMID: 23691113
Microtubules are the main constituents of mitotic spindles. They are nucleated in large amounts during spindle assembly, from multiprotein complexes containing γ-tubulin and associated γ-tubulin complex proteins (GCPs). With the...
18.
Remy M, Merdes A, Gregory-Pauron L
Prog Mol Biol Transl Sci
. 2013 May;
117:511-30.
PMID: 23663981
Microtubules are among the main constituents of the cytoskeleton. They are assembled from dimers of alpha- and beta-tubulin. This assembly occurs preferentially at organizing centers such as the centrosomes, catalyzed...
19.
Kollman J, Merdes A, Mourey L, Agard D
Nat Rev Mol Cell Biol
. 2011 Oct;
12(11):709-21.
PMID: 21993292
Microtubule nucleation is regulated by the γ-tubulin ring complex (γTuRC) and related γ-tubulin complexes, providing spatial and temporal control over the initiation of microtubule growth. Recent structural work has shed...
20.
Merdes A, De Mey J
Methods Mol Biol
. 2011 Jul;
777:209-21.
PMID: 21773931
The movement of chromosomes in mitosis requires spindle microtubules, as well as a set of specific motor proteins located at the kinetochores of the chromosomes. The exact mechanisms of chromosome...