Andreas Merdes
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Explore the profile of Andreas Merdes including associated specialties, affiliations and a list of published articles.
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45
Citations
2679
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Recent Articles
21.
Puram S, Kim A, Ikeuchi Y, Wilson-Grady J, Merdes A, Gygi S, et al.
Nat Neurosci
. 2011 Jul;
14(8):973-83.
PMID: 21725312
The protein kinase calcium/calmodulin-dependent kinase II (CaMKII) predominantly consists of the α and β isoforms in the brain. Although CaMKIIα functions have been elucidated, the isoform-specific catalytic functions of CaMKIIβ...
22.
Guillet V, Knibiehler M, Gregory-Pauron L, Remy M, Chemin C, Raynaud-Messina B, et al.
Nat Struct Mol Biol
. 2011 Jul;
18(8):915-9.
PMID: 21725292
Microtubule nucleation in all eukaryotes involves γ-tubulin small complexes (γTuSCs) that comprise two molecules of γ-tubulin bound to γ-tubulin complex proteins (GCPs) GCP2 and GCP3. In many eukaryotes, multiple γTuSCs...
23.
Peyre E, Jaouen F, Saadaoui M, Haren L, Merdes A, Durbec P, et al.
J Cell Biol
. 2011 Mar;
193(1):141-54.
PMID: 21444683
To maintain tissue architecture, epithelial cells divide in a planar fashion, perpendicular to their main polarity axis. As the centrosome resumes an apical localization in interphase, planar spindle orientation is...
24.
Fant X, Srsen V, Espigat-Georger A, Merdes A
PLoS One
. 2009 Dec;
4(12):e8303.
PMID: 20011525
Background: In differentiating myoblasts, the microtubule network is reorganized from a centrosome-bound, radial array into parallel fibres, aligned along the long axis of the cell. Concomitantly, proteins of the centrosome...
25.
Bouissou A, Verollet C, Sousa A, Sampaio P, Wright M, Sunkel C, et al.
J Cell Biol
. 2009 Dec;
187(3):327-34.
PMID: 19948476
gamma-Tubulin is critical for the initiation and regulation of microtubule (MT) assembly. In Drosophila melanogaster, it acts within two main complexes: the gamma-tubulin small complex (gamma-TuSC) and the gamma-tubulin ring...
26.
Haren L, Gnadt N, Wright M, Merdes A
BMC Res Notes
. 2009 Apr;
2:64.
PMID: 19400937
Background: NuMA is a protein that has been previously shown to play a role in focusing microtubules at the mitotic spindle poles. However, most previous work relies on experimental methods...
27.
Srsen V, Fant X, Heald R, Rabouille C, Merdes A
BMC Cell Biol
. 2009 Apr;
10:28.
PMID: 19383121
Background: Muscle fibres are formed by elongation and fusion of myoblasts into myotubes. During this differentiation process, the cytoskeleton is reorganized, and proteins of the centrosome re-localize to the surface...
28.
Fant X, Gnadt N, Haren L, Merdes A
J Cell Sci
. 2009 Mar;
122(Pt 8):1134-44.
PMID: 19299467
To investigate changes at the centrosome during the cell cycle, we analyzed the composition of the pericentriolar material from unsynchronized and S-phase-arrested cells by gel electrophoresis and mass spectrometry. We...
29.
Tillement V, Haren L, Roullet N, Etievant C, Merdes A
Mol Cancer
. 2009 Feb;
8:10.
PMID: 19243593
Background: NEDD1 is a protein that binds to the gamma-tubulin ring complex, a multiprotein complex at the centrosome and at the mitotic spindle that mediates the nucleation of microtubules. Results:...
30.
Tillement V, Remy M, Raynaud-Messina B, Mazzolini L, Haren L, Merdes A
Biol Cell
. 2008 Dec;
101(1):1-11.
PMID: 19055485
Mitotic spindle formation in animal cells involves microtubule nucleation from two centrosomes that are positioned at opposite sides of the nucleus. Microtubules are captured by the kinetochores and stabilized. In...