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Andrea L Hevener

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Articles 69
Citations 5782
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Recent Articles
1.
Kuchel G, Hevener A, Ruby J, Sebastiani P, Kumar V
J Gerontol A Biol Sci Med Sci . 2025 Mar; 80(4). PMID: 40052564
Historically, aging research has focused primarily on the study of differences in means of varied measures obtained at different ages. However, growing evidence has shown that for many parameters, variability...
2.
Fitzgerald L, Reynoso Spurrier C, Lau N, Melamed M, Burnett L, Meyer G, et al.
bioRxiv . 2025 Jan; PMID: 39868315
Mitochondria are key regulators of metabolism and ATP supply in skeletal muscle, while circadian rhythms influence many physiological processes. However, whether mitochondrial function is intrinsically regulated in a circadian manner...
3.
Vinciguerra D, Rajalakshmi P S , Yang J, Georgiou P, Snell K, Pesenti T, et al.
ACS Cent Sci . 2024 Dec; 10(11):2036-2047. PMID: 39634211
While glucose-responsive insulin delivery systems are in widespread clinical use to treat insulin insufficiency, the on-demand supplementation of glucagon for acute hypoglycemia treatment remains understudied. A self-regulated glucagon release material...
4.
Lee-Odegard S, Hjorth M, Olsen T, Moen G, Daubney E, Evans D, et al.
Elife . 2024 Aug; 13. PMID: 39190027
Background: Physical activity has been associated with preventing the development of type 2 diabetes and atherosclerotic cardiovascular disease. However, our understanding of the precise molecular mechanisms underlying these effects remains...
5.
Schenk S, Sagendorf T, Many G, Lira A, de Sousa L, Bae D, et al.
Function (Oxf) . 2024 Jul; 5(4). PMID: 38984994
While regular physical activity is a cornerstone of health, wellness, and vitality, the impact of endurance exercise training on molecular signaling within and across tissues remains to be delineated. The...
6.
Devarajan A, Wang K, Lokhandwala Z, Emamimeybodi M, Shannon K, Tompkins J, et al.
JCI Insight . 2024 Jun; 9(14). PMID: 38885308
Parasympathetic dysfunction after chronic myocardial infarction (MI) is known to predispose ventricular tachyarrhythmias (ventricular tachycardia/ventricular fibrillation [VT/VF]). VT/VF after MI is more common in males than females. The mechanisms underlying...
7.
Puente E, Sivasankaran R, Vinciguerra D, Yang J, Lower H, Hevener A, et al.
RSC Appl Polym . 2024 May; 2(3):473-482. PMID: 38800515
Glucagon is a peptide hormone that acts receptor-mediated signaling predominantly in the liver to raise glucose levels by hepatic glycogen breakdown or conversion of noncarbohydrate, 3 carbon precursors to glucose...
8.
Amar D, Gay N, Jimenez-Morales D, Jean Beltran P, Ramaker M, Raja A, et al.
Cell Metab . 2024 May; 36(6):1411-1429.e10. PMID: 38701776
Mitochondria have diverse functions critical to whole-body metabolic homeostasis. Endurance training alters mitochondrial activity, but systematic characterization of these adaptations is lacking. Here, the Molecular Transducers of Physical Activity Consortium...
9.
Many G, Sanford J, Sagendorf T, Hou Z, Nigro P, Whytock K, et al.
Nat Metab . 2024 May; 6(5):963-979. PMID: 38693320
Subcutaneous white adipose tissue (scWAT) is a dynamic storage and secretory organ that regulates systemic homeostasis, yet the impact of endurance exercise training (ExT) and sex on its molecular landscape...
10.
Zhou Z, Ma A, Moore T, Wolf D, Yang N, Tran P, et al.
Sci Adv . 2024 Apr; 10(14):eadl0389. PMID: 38569044
The dynamin-related guanosine triphosphatase, Drp1 (encoded by ), plays a central role in mitochondrial fission and is requisite for numerous cellular processes; however, its role in muscle metabolism remains unclear....