Andrea Hinas
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Explore the profile of Andrea Hinas including associated specialties, affiliations and a list of published articles.
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16
Citations
251
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Recent Articles
1.
Lind M, Mautz B, Carlsson H, Hinas A, Gudmunds E, Maklakov A
Aging Cell
. 2024 Jul;
23(11):e14290.
PMID: 39082232
Germline regulates the expression of life-history traits and mediates the trade-off between reproduction and somatic maintenance. However, germline maintenance in itself can be costly, and the costs can vary between...
2.
Dube F, Delhomme N, Martin F, Hinas A, Abrink M, Svard S, et al.
PLoS One
. 2024 Feb;
19(2):e0298039.
PMID: 38359071
Anthelmintic resistance in equine parasite Parascaris univalens, compromises ivermectin (IVM) effectiveness and necessitates an in-depth understanding of its resistance mechanisms. Most research, primarily focused on holistic gene expression analyses, may...
3.
Dube F, Hinas A, Delhomme N, Abrink M, Svard S, Tyden E
PLoS One
. 2023 May;
18(5):e0285262.
PMID: 37141255
Parasitic nematodes pose a significant threat to human and animal health, as well as cause economic losses in the agricultural sector. The use of anthelmintic drugs, such as Ivermectin (IVM),...
4.
Dube F, Hinas A, Roy S, Martin F, Abrink M, Svard S, et al.
Parasit Vectors
. 2022 May;
15(1):158.
PMID: 35513885
Background: The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infecting horses but anthelmintic resistance undermines treatment approaches. The molecular mechanisms underlying drug activity and resistance remain...
5.
Lind M, Ravindran S, Sekajova Z, Carlsson H, Hinas A, Maklakov A
Evol Lett
. 2019 Apr;
3(2):207-216.
PMID: 31007945
Classical theory maintains that ageing evolves via energy trade-offs between reproduction and survival leading to accumulation of unrepaired cellular damage with age. In contrast, the emerging new theory postulates that...
6.
Maklakov A, Carlsson H, Denbaum P, Lind M, Mautz B, Hinas A, et al.
Proc Biol Sci
. 2017 Jun;
284(1856).
PMID: 28615498
Evolutionary theory of ageing maintains that increased allocation to early-life reproduction results in reduced somatic maintenance, which is predicted to compromise longevity and late-life reproduction. This prediction has been challenged...
7.
Zhao Y, Holmgren B, Hinas A
RNA
. 2016 Dec;
23(3):297-307.
PMID: 27974622
Small RNA pathways, including RNA interference (RNAi), play crucial roles in regulation of gene expression. Initially considered to be cytoplasmic, these processes have later been demonstrated to associate with membranes....
8.
Dierker T, Shao C, Haitina T, Zaia J, Hinas A, Kjellen L
Sci Rep
. 2016 Oct;
6:34662.
PMID: 27703236
Proteoglycans are proteins that carry sulfated glycosaminoglycans (GAGs). They help form and maintain morphogen gradients, guiding cell migration and differentiation during animal development. While no sulfated GAGs have been found...
9.
Crona M, Avesson L, Sahlin M, Lundin D, Hinas A, Klose R, et al.
J Biol Chem
. 2013 Feb;
288(12):8198-8208.
PMID: 23372162
Ribonucleotide reductases (RNRs) catalyze the only pathway for de novo synthesis of deoxyribonucleotides needed for DNA replication and repair. The vast majority of eukaryotes encodes only a class I RNR,...
10.
Hinas A, Wright A, Hunter C
Curr Biol
. 2012 Sep;
22(20):1938-43.
PMID: 22981770
In the nematode C. elegans, RNAi silencing signals are efficiently taken up from the environment and transported between cells and tissues. Previous studies implicating endosomal proteins in systemic RNAi lack...