Alexei A Maklakov
Overview
Explore the profile of Alexei A Maklakov including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
77
Citations
1471
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sultanova Z, Shen A, Hencel K, Carlsson H, Crighton Z, Clifton D, et al.
Aging Cell
. 2025 Jan;
e14481.
PMID: 39853894
The developmental theory of ageing proposes that age-specific decline in the force of natural selection results in suboptimal levels of gene expression in adulthood, leading to functional senescence. This theory...
2.
Lind M, Mautz B, Carlsson H, Hinas A, Gudmunds E, Maklakov A
Aging Cell
. 2024 Jul;
23(11):e14290.
PMID: 39082232
Germline regulates the expression of life-history traits and mediates the trade-off between reproduction and somatic maintenance. However, germline maintenance in itself can be costly, and the costs can vary between...
3.
Duxbury E, Carlsson H, Kimberley A, Ridge Y, Johnson K, Maklakov A
Geroscience
. 2024 Apr;
46(6):5767-5780.
PMID: 38589671
Reduced insulin/IGF-1 signalling (rIIS) improves survival across diverse taxa and there is a growing interest in its role in regulating immune function. Whilst rIIS can improve anti-bacterial resistance, the consequences...
4.
Lemaitre J, Moorad J, Gaillard J, Maklakov A, Nussey D
PLoS Biol
. 2024 Feb;
22(2):e3002513.
PMID: 38412150
Why and how we age are 2 intertwined questions that have fascinated scientists for many decades. However, attempts to answer these questions remain compartmentalized, preventing a comprehensive understanding of the...
5.
Chen H, Krieg T, Mautz B, Jolly C, Scofield D, Maklakov A, et al.
Evol Lett
. 2023 Dec;
7(6):478-489.
PMID: 38045724
The effect of parental age on germline mutation rate across generations is not fully understood. While some studies report a positive linear relationship of mutation rate with increasing age, others...
6.
Rostant W, Mason J, West N, Maklakov A, Chapman T
J Gerontol A Biol Sci Med Sci
. 2023 Sep;
78(12):2230-2239.
PMID: 37694551
Males and females rarely express the same length of life. Here, we studied how sociosexual exposure shapes male and female age-specific mortality rates in Drosophila melanogaster. We maintained focal females...
7.
Ivimey-Cook E, Murray D, de Coriolis J, Edden N, Immler S, Maklakov A
Proc Biol Sci
. 2023 May;
290(1998):20230872.
PMID: 37132242
No abstract available.
8.
Ivimey-Cook E, Murray D, de Coriolis J, Edden N, Immler S, Maklakov A
Proc Biol Sci
. 2023 Apr;
290(1996):20221556.
PMID: 37040805
Fasting increases lifespan in invertebrates, improves biomarkers of health in vertebrates and is increasingly proposed as a promising route to improve human health. Nevertheless, little is known about how fasted...
9.
Duxbury E, Carlsson H, Sales K, Sultanova Z, Immler S, Chapman T, et al.
Evolution
. 2022 Oct;
76(12):2829-2845.
PMID: 36199198
Adulthood-only downregulation of insulin/IGF-1 signaling (IIS), an evolutionarily conserved pathway regulating resource allocation between somatic maintenance and reproduction, increases life span without fecundity cost in the nematode, Caenorhabditis elegans. However,...
10.
Sultanova Z, Ivimey-Cook E, Chapman T, Maklakov A
Proc Biol Sci
. 2021 Nov;
288(1963):20211787.
PMID: 34814748
Dietary restriction (DR) improves survival across a wide range of taxa yet remains poorly understood. The key unresolved question is whether this evolutionarily conserved response to temporary lack of food...