Hanne Carlsson
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Explore the profile of Hanne Carlsson including associated specialties, affiliations and a list of published articles.
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13
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99
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Recent Articles
1.
Sultanova Z, Shen A, Hencel K, Carlsson H, Crighton Z, Clifton D, et al.
Aging Cell
. 2025 Jan;
e14481.
PMID: 39853894
The developmental theory of ageing proposes that age-specific decline in the force of natural selection results in suboptimal levels of gene expression in adulthood, leading to functional senescence. This theory...
2.
Lind M, Mautz B, Carlsson H, Hinas A, Gudmunds E, Maklakov A
Aging Cell
. 2024 Jul;
23(11):e14290.
PMID: 39082232
Germline regulates the expression of life-history traits and mediates the trade-off between reproduction and somatic maintenance. However, germline maintenance in itself can be costly, and the costs can vary between...
3.
Duxbury E, Carlsson H, Kimberley A, Ridge Y, Johnson K, Maklakov A
Geroscience
. 2024 Apr;
46(6):5767-5780.
PMID: 38589671
Reduced insulin/IGF-1 signalling (rIIS) improves survival across diverse taxa and there is a growing interest in its role in regulating immune function. Whilst rIIS can improve anti-bacterial resistance, the consequences...
4.
Duxbury E, Carlsson H, Sales K, Sultanova Z, Immler S, Chapman T, et al.
Evolution
. 2022 Oct;
76(12):2829-2845.
PMID: 36199198
Adulthood-only downregulation of insulin/IGF-1 signaling (IIS), an evolutionarily conserved pathway regulating resource allocation between somatic maintenance and reproduction, increases life span without fecundity cost in the nematode, Caenorhabditis elegans. However,...
5.
Aldholmi M, Ahmad R, Carretero-Molina D, Perez-Victoria I, Martin J, Reyes F, et al.
Angew Chem Int Ed Engl
. 2022 Mar;
61(23):e202203175.
PMID: 35325497
By limiting the nitrogen source to glutamic acid, we isolated cyclic peptides from Euglena gracilis containing asparagine and non-proteinogenic amino acids. Structure elucidation was accomplished through spectroscopic methods, mass spectrometry...
6.
Travers L, Carlsson H, Lind M, Maklakov A
Proc Biol Sci
. 2021 Oct;
288(1960):20211843.
PMID: 34641727
Old parental age is commonly associated with negative effects on offspring life-history traits. Such parental senescence effects are predicted to have a cumulative detrimental effect over successive generations. However, old...
7.
Carlsson H, Ivimey-Cook E, Duxbury E, Edden N, Sales K, Maklakov A
Evol Lett
. 2021 Oct;
5(5):551-564.
PMID: 34621540
The theory that ageing evolves because of competitive resource allocation between the soma and the germline has been challenged by studies showing that somatic maintenance can be improved without impairing...
8.
Ivimey-Cook E, Sales K, Carlsson H, Immler S, Chapman T, Maklakov A
Proc Biol Sci
. 2021 May;
288(1950):20210701.
PMID: 33975472
Dietary restriction (DR) increases lifespan in a broad variety of organisms and improves health in humans. However, long-term transgenerational consequences of dietary interventions are poorly understood. Here, we investigated the...
9.
Lind M, Carlsson H, Duxbury E, Ivimey-Cook E, Maklakov A
Proc Biol Sci
. 2021 Feb;
288(1944):20201728.
PMID: 33529563
Ageing evolves because the force of selection on traits declines with age but the proximate causes of ageing are incompletely understood. The 'disposable soma' theory of ageing (DST) upholds that...
10.
Lind M, Zwoinska M, Andersson J, Carlsson H, Krieg T, Larva T, et al.
Evol Lett
. 2020 Aug;
4(4):371-381.
PMID: 32774885
Theory maintains that when future environment is predictable, parents should adjust the phenotype of their offspring to match the anticipated environment. The plausibility of positive anticipatory parental effects is hotly...