Staffan Svard
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Explore the profile of Staffan Svard including associated specialties, affiliations and a list of published articles.
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29
Citations
392
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Recent Articles
1.
Akdeniz Z, Havelka M, Stoklasa M, Jimenez-Gonzalez A, Zarsky V, Xu F, et al.
Sci Data
. 2025 Feb;
12(1):192.
PMID: 39893204
Diplomonads are anaerobic, flagellated protists, being part of the Metamonada group of Eukaryotes. Diplomonads either live as endobionts (parasites and commensals) of animals or free-living in low-oxygen environments. Genomic information...
2.
Dube F, Delhomme N, Martin F, Hinas A, Abrink M, Svard S, et al.
PLoS One
. 2024 Feb;
19(2):e0298039.
PMID: 38359071
Anthelmintic resistance in equine parasite Parascaris univalens, compromises ivermectin (IVM) effectiveness and necessitates an in-depth understanding of its resistance mechanisms. Most research, primarily focused on holistic gene expression analyses, may...
3.
Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis
Motyckova A, Voleman L, Najdrova V, Arbonova L, Benda M, Dohnalek V, et al.
PLoS Pathog
. 2023 Oct;
19(10):e1010773.
PMID: 37792908
Mitochondrial metabolism is entirely dependent on the biosynthesis of the [4Fe-4S] clusters, which are part of the subunits of the respiratory chain. The mitochondrial late ISC pathway mediates the formation...
4.
Dube F, Hinas A, Delhomme N, Abrink M, Svard S, Tyden E
PLoS One
. 2023 May;
18(5):e0285262.
PMID: 37141255
Parasitic nematodes pose a significant threat to human and animal health, as well as cause economic losses in the agricultural sector. The use of anthelmintic drugs, such as Ivermectin (IVM),...
5.
Santos R, Astvaldsson A, Pipaliya S, Zumthor J, Dacks J, Svard S, et al.
BMC Biol
. 2022 Sep;
20(1):206.
PMID: 36127707
Background: Giardia lamblia, a parasitic protist of the Metamonada supergroup, has evolved one of the most diverged endocytic compartment systems investigated so far. Peripheral endocytic compartments, currently known as peripheral...
6.
Dube F, Hinas A, Roy S, Martin F, Abrink M, Svard S, et al.
Parasit Vectors
. 2022 May;
15(1):158.
PMID: 35513885
Background: The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infecting horses but anthelmintic resistance undermines treatment approaches. The molecular mechanisms underlying drug activity and resistance remain...
7.
Krakovka S, Ribacke U, Miyamoto Y, Eckmann L, Svard S
Front Microbiol
. 2022 Feb;
13:834008.
PMID: 35222342
Metronidazole (MTZ) is a clinically important antimicrobial agent that is active against both bacterial and protozoan organisms. MTZ has been used extensively for more than 60 years and until now...
8.
Li Z, Peirasmaki D, Svard S, Abrink M
Front Immunol
. 2021 Aug;
12:677722.
PMID: 34335577
The proteoglycan serglycin (SG) is expressed by different innate and adaptive immune cells, mast cells, macrophages, neutrophils, and cytotoxic T lymphocytes, where SG contributes to correct granule storage and extracellular...
9.
Buret A, Caccio S, Favennec L, Svard S
Parasite
. 2020 Aug;
27:49.
PMID: 32788035
Although Giardia duodenalis is recognized as one of the leading causes of parasitic human diarrhea in the world, knowledge of the mechanisms of infection is limited, as the pathophysiological consequences...
10.
Li Z, Peirasmaki D, Svard S, Abrink M
Cells
. 2020 Apr;
9(4).
PMID: 32283818
Mast cells have been shown to affect the control of infections with the protozoan parasite . Recently, we demonstrated that excretory-secretory proteins inhibited the activity of the connective tissue mast...