Andrea Gazzo
Overview
Explore the profile of Andrea Gazzo including associated specialties, affiliations and a list of published articles.
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17
Citations
307
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Recent Articles
1.
Jalan M, Brambati A, Shah H, McDermott N, Patel J, Zhu Y, et al.
bioRxiv
. 2025 Mar;
PMID: 40060534
Double-strand breaks (DSBs) are toxic lesions that lead to genome instability. While canonical DSB repair pathways typically operate independently of RNA, emerging evidence suggests that RNA:DNA hybrids and transcripts near...
2.
Lasso G, Grodus M, Valencia E, DeJesus V, Liang E, Delwel I, et al.
Cell Host Microbe
. 2025 Jan;
33(2):294-313.e11.
PMID: 39818205
Evidence suggests that bats are important hosts of filoviruses, yet the specific species involved remain largely unidentified. Niemann-Pick C1 (NPC1) is an essential entry receptor, with amino acid variations influencing...
3.
Brodeur M, Dopeso H, Zhu Y, Longhini A, Gazzo A, Sun S, et al.
Sci Adv
. 2024 Dec;
10(49):eadk4851.
PMID: 39630912
Cell-intrinsic mechanisms of immunogenicity in ovarian cancer (OC) are not well understood. Damaging mutations in the SWI/SNF chromatin remodeling complex, such as (BRG1), are associated with improved response to immune...
4.
Moufarrij S, Gazzo A, Rana S, Selenica P, Abu-Rustum N, Ellenson L, et al.
Gynecol Oncol
. 2024 Sep;
191:1-9.
PMID: 39276497
Objective: Endometrial carcinoma (EC) has different molecular subtypes associated with varied prognosis. We sought to characterize the molecular features of ECs with POLE hotspot mutations and concurrent mismatch repair (MMR)...
5.
OConnor C, Harrold E, Lin D, Walch H, Gazzo A, Ranganathan M, et al.
JAMA Oncol
. 2024 Sep;
10(11):1511-1518.
PMID: 39235819
Importance: Microsatellite (MS) instability (MSI-H) occurs frequently in Lynch syndrome (LS)-associated tumors and is associated with response to immune checkpoint blockade (ICB) therapy. MSI-H is conferred by germline or somatic...
6.
Zhu Y, Pei X, Novaj A, Setton J, Bronder D, Derakhshan F, et al.
Genome Med
. 2024 Aug;
16(1):108.
PMID: 39198848
Background: Pathogenic BRCA1 or BRCA2 germline mutations contribute to hereditary breast, ovarian, prostate, and pancreatic cancer. Paradoxically, bi-allelic inactivation of BRCA1 or BRCA2 (bBRCA1/2) is embryonically lethal and decreases cellular...
7.
Schwartz C, Marra A, Selenica P, Gazzo A, Tan K, Ross D, et al.
Mod Pathol
. 2024 Jun;
37(8):100541.
PMID: 38897452
Genetic alterations in the retinoblastoma susceptibility gene (RB1) are present in up to 40% of triple-negative breast cancers (BCs) and frequent in tumors with neuroendocrine differentiation, including small cell neuroendocrine...
8.
Gupta A, Gazzo A, Selenica P, Safonov A, Pareja F, da Silva E, et al.
bioRxiv
. 2024 May;
PMID: 38746158
Acquired genetic alterations commonly drive resistance to endocrine and targeted therapies in metastatic breast cancer , however the underlying processes engendering these diverse alterations are largely uncharacterized. To identify the...
9.
Maximo V, Melo M, Zhu Y, Gazzo A, Sobrinho Simoes M, Da Cruz Paula A, et al.
Endocr Relat Cancer
. 2023 Nov;
31(2).
PMID: 38015791
The genetic repertoire of primary thyroid cancers (TCs) is well documented, but there is a considerable lack of molecular profiling in metastatic TCs. Here, we retrieved and analyzed the molecular...
10.
Brodeur M, Dopeso H, Zhu Y, Longhini A, Gazzo A, Sun S, et al.
bioRxiv
. 2023 Aug;
PMID: 37609261
Cell-intrinsic mechanisms of immunogenicity in ovarian cancer (OC) are not well understood. The presence of damaging mutations in the SWI/SNF chromatin remodeling complex, such as the (BRG1) catalytic subunit, has...