Andre Fedier
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Explore the profile of Andre Fedier including associated specialties, affiliations and a list of published articles.
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618
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Recent Articles
1.
Labrosse K, Lombardo F, Rimmer N, Nunez Lopez M, Fedier A, Heinzelmann-Schwarz V, et al.
STAR Protoc
. 2024 Aug;
5(3):103274.
PMID: 39172645
Three-dimensional (3D) ex vivo cultures allow the study of cancer progression and drug resistance mechanisms. Here, we present a protocol for measuring on-target drug sensitivity in a scaffold-free 3D culture...
2.
Schwab F, Scheidmann M, Ozimski L, Kling A, Armbrecht L, Ryser T, et al.
Microsyst Nanoeng
. 2022 Dec;
8:130.
PMID: 36561926
Cancer patients with advanced disease are characterized by intrinsic challenges in predicting drug response patterns, often leading to ineffective treatment. Current clinical practice for treatment decision-making is commonly based on...
3.
Coelho R, Tozzi A, Disler M, Lombardo F, Fedier A, Nunez Lopez M, et al.
Cell Death Dis
. 2022 Oct;
13(10):909.
PMID: 36307400
PARP inhibitors (PARPi) have revolutionized the therapeutic landscape of epithelial ovarian cancer (EOC) treatment with outstanding benefits in regard to progression-free survival, especially in patients either carrying BRCA1/2 mutations or...
4.
Cumin C, Huang Y, Rossdam C, Ruoff F, Posada Cespedes S, Liang C, et al.
Cell Rep
. 2022 Aug;
40(7):111181.
PMID: 35977490
The molecular repertoire promoting cancer cell plasticity is not fully elucidated. Here, we propose that glycosphingolipids (GSLs), specifically the globo and ganglio series, correlate and promote the transition between epithelial...
5.
Fedier A, Maggi N, Tozzi A, Disler M, Coelho R, Jacob F, et al.
Int J Oncol
. 2022 Jun;
61(1).
PMID: 35642662
Poly (ADP‑ribose) polymerase (PARP)‑inhibitors (PARPi) such as olaparib and niraparib are currently used as a treatment option for ‑deficient tumors and also show efficacy in platinum‑sensitive tumors. However, resistance to...
6.
Huang Y, Liang C, Ritz D, Coelho R, Septiadi D, Estermann M, et al.
Elife
. 2020 Oct;
9.
PMID: 33026975
The extracellular matrix (ECM) plays critical roles in tumor progression and metastasis. However, the contribution of ECM proteins to early metastatic onset in the peritoneal cavity remains unexplored. Here, we...
7.
Montavon C, Stricker G, Schoetzau A, Heinzelmann-Schwarz V, Jacob F, Fedier A
J Cancer Res Clin Oncol
. 2019 Oct;
145(11):2737-2749.
PMID: 31586262
Background: Large tumor suppressor (LATS) proteins are putative tumor suppressors and poorly expressed associated with poor outcome in many cancers. A recent immunohistochemistry study showed that LATS protein expression correlated...
8.
Montavon C, Mirza U, Fedier A, Schoetzau A, Zanetti Dallenbach R, Heinzelmann-Schwarz V
Exp Ther Med
. 2018 May;
15(5):4199-4204.
PMID: 29725367
Peritoneal biopsies (PB) and peritoneal washing (PW) are routine measures in abdominal staging of gynecological malignancies and are used particularly for the assessment of occult microscopic tumor spread to the...
9.
Sartorius C, Schoetzau A, Kettelhack H, Fink D, Hacker N, Fedier A, et al.
PLoS One
. 2018 Mar;
13(3):e0195213.
PMID: 29596526
The relationship between ABO blood groups (BG) and risk of incidence in cancers including gynecological cancers has been widely studied, showing increased incidence risk for BG A patients. As available...
10.
Jacob F, Alam S, Konantz M, Liang C, Kohler R, Everest-Dass A, et al.
Cancer Res
. 2018 Mar;
78(11):2952-2965.
PMID: 29572228
The reversible transitions of cancer cells between epithelial and mesenchymal states comprise cellular and molecular processes essential for local tumor growth and respective dissemination. We report here that globoside glycosphingolipid...