Andre Fedier
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Explore the profile of Andre Fedier including associated specialties, affiliations and a list of published articles.
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40
Citations
618
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Recent Articles
11.
Kohler R, Kettelhack H, Knipprath-Meszaros A, Fedier A, Schoetzau A, Jacob F, et al.
Gynecol Oncol
. 2017 Feb;
145(1):159-166.
PMID: 28214016
Objective: Maternal embryonic leucine-zipper kinase (MELK) shows oncogenic properties in basal-like breast cancer, a cancer subtype sharing common molecular features with high-grade serous ovarian cancer. We examined the potential of...
12.
Pochechueva T, Chinarev A, Schoetzau A, Fedier A, Bovin N, Hacker N, et al.
PLoS One
. 2016 Oct;
11(10):e0164230.
PMID: 27764122
Altered levels of naturally occurring anti-glycan antibodies (AGA) circulating in human blood plasma are found in different pathologies including cancer. Here the levels of AGA directed against 22 negatively charged...
13.
Kohler R, Anugraham M, Nunez Lopez M, Xiao C, Schoetzau A, Hettich T, et al.
Oncotarget
. 2016 Jul;
7(32):51674-51686.
PMID: 27429195
Bisecting GlcNAc on N-glycoproteins is described in E-cadherin-, EGF-, Wnt- and integrin- cancer-associated signaling pathways. However, the mechanisms regulating bisecting GlcNAc expression are not clear. Bisecting GlcNAc is attached to...
14.
Decollogne S, Joshi S, Chung S, Luk P, Yeo R, Nixdorf S, et al.
Gynecol Oncol
. 2015 Jun;
138(2):363-71.
PMID: 26080289
Objective: The purpose of this study was to test PENAO, a promising new organoarsenical that is in phase 1 testing in patients with solid tumours, on a range of ovarian...
15.
Alam S, Fedier A, Kohler R, Jacob F
Glycobiology
. 2015 Feb;
25(4):351-6.
PMID: 25715344
Glucosylceramide synthase (GCS) catalyzes the first committed step in the biosynthesis of glucosylceramide (GlcCer)-related glycosphingolipids (GSLs). Although inhibitors of GCS, PPMP and PDMP have been widely used to elucidate their...
16.
Jacob F, Hitchins M, Fedier A, Brennan K, Nixdorf S, Hacker N, et al.
BMC Mol Biol
. 2014 Oct;
15:24.
PMID: 25294702
Background: The GBGT1 gene encodes the globoside alpha-1,3-N-acetylgalactosaminyltransferase 1. This enzyme catalyzes the last step in the multi-step biosynthesis of the Forssman (Fs) antigen, a pentaglycosyl ceramide of the globo...
17.
Pochechueva T, Chinarev A, Bovin N, Fedier A, Jacob F, Heinzelmann-Schwarz V
J Immunol Methods
. 2014 Jul;
412:42-52.
PMID: 24995712
Glycan-based suspension array (SGA) is an "in-house" developed multi-target immunoassay, employing commercially available fluorescent microbeads as a solid support for unique chemically synthesized glycopolymers which capture naturally occurring human anti-glycan...
18.
Pochechueva T, Jacob F, Fedier A, Heinzelmann-Schwarz V
Metabolites
. 2014 Jun;
2(4):913-39.
PMID: 24957768
Glycans are important partners in many biological processes, including carcinogenesis. The rapidly developing field of functional glycomics becomes one of the frontiers of biology and biomedicine. Aberrant glycosylation of proteins...
19.
Heinzelmann-Schwarz V, Nixdorf S, Valadan M, Diczbalis M, Olivier J, Otton G, et al.
Int J Mol Med
. 2014 Feb;
33(4):784-94.
PMID: 24535703
Vulvar melanoma is the second most common vulvar cancer. Patients with vulvar melanoma usually present with the disease at a late stage and have a poor prognosis. The prognostic predictors...
20.
Imesch P, Scheiner D, Szabo E, Fink D, Fedier A
Exp Ther Med
. 2013 Oct;
6(3):786-790.
PMID: 24137266
Polycationic cell-penetrating peptides (CPPs) deliver macromolecules into cells without losing the functional properties of the cargoed macromolecule. The aim of this study was to determine whether exogenous cytochrome is delivered...