Monica Nunez Lopez
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Explore the profile of Monica Nunez Lopez including associated specialties, affiliations and a list of published articles.
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9
Citations
128
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Recent Articles
1.
Labrosse K, Lombardo F, Rimmer N, Nunez Lopez M, Fedier A, Heinzelmann-Schwarz V, et al.
STAR Protoc
. 2024 Aug;
5(3):103274.
PMID: 39172645
Three-dimensional (3D) ex vivo cultures allow the study of cancer progression and drug resistance mechanisms. Here, we present a protocol for measuring on-target drug sensitivity in a scaffold-free 3D culture...
2.
Generation of endogenously tagged E-cadherin cells using gene editing via non-homologous end joining
Rimmer N, Liang C, Coelho R, Nunez Lopez M, Jacob F
STAR Protoc
. 2023 May;
4(2):102305.
PMID: 37178110
We provide a protocol using non-homologous end joining to integrate an oligonucleotide sequence of a fluorescence protein at the CDH1 locus encoding for the epithelial glycoprotein E-cadherin. We describe steps...
3.
Coelho R, Tozzi A, Disler M, Lombardo F, Fedier A, Nunez Lopez M, et al.
Cell Death Dis
. 2022 Oct;
13(10):909.
PMID: 36307400
PARP inhibitors (PARPi) have revolutionized the therapeutic landscape of epithelial ovarian cancer (EOC) treatment with outstanding benefits in regard to progression-free survival, especially in patients either carrying BRCA1/2 mutations or...
4.
Cumin C, Huang Y, Rossdam C, Ruoff F, Posada Cespedes S, Liang C, et al.
Cell Rep
. 2022 Aug;
40(7):111181.
PMID: 35977490
The molecular repertoire promoting cancer cell plasticity is not fully elucidated. Here, we propose that glycosphingolipids (GSLs), specifically the globo and ganglio series, correlate and promote the transition between epithelial...
5.
Huang Y, Liang C, Ritz D, Coelho R, Septiadi D, Estermann M, et al.
Elife
. 2020 Oct;
9.
PMID: 33026975
The extracellular matrix (ECM) plays critical roles in tumor progression and metastasis. However, the contribution of ECM proteins to early metastatic onset in the peritoneal cavity remains unexplored. Here, we...
6.
Coelho R, Ricardo S, Amaral A, Huang Y, Nunes M, Neves J, et al.
Oncogenesis
. 2020 Jul;
9(6):61.
PMID: 32612258
Peritoneal dissemination is a particular form of metastasis typically observed in ovarian cancer and the major cause for poor patient's outcome. Identification of the molecular players involved in ovarian cancer...
7.
Jacob F, Alam S, Konantz M, Liang C, Kohler R, Everest-Dass A, et al.
Cancer Res
. 2018 Mar;
78(11):2952-2965.
PMID: 29572228
The reversible transitions of cancer cells between epithelial and mesenchymal states comprise cellular and molecular processes essential for local tumor growth and respective dissemination. We report here that globoside glycosphingolipid...
8.
Alam S, Anugraham M, Huang Y, Kohler R, Hettich T, Winkelbach K, et al.
Sci Rep
. 2017 Mar;
7:45367.
PMID: 28358117
The (neo-) lacto series glycosphingolipids (nsGSLs) comprise of glycan epitopes that are present as blood group antigens, act as primary receptors for human pathogens and are also increasingly associated with...
9.
Kohler R, Anugraham M, Nunez Lopez M, Xiao C, Schoetzau A, Hettich T, et al.
Oncotarget
. 2016 Jul;
7(32):51674-51686.
PMID: 27429195
Bisecting GlcNAc on N-glycoproteins is described in E-cadherin-, EGF-, Wnt- and integrin- cancer-associated signaling pathways. However, the mechanisms regulating bisecting GlcNAc expression are not clear. Bisecting GlcNAc is attached to...