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Ana Sevilla

Explore the profile of Ana Sevilla including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 1458
Followers 0
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Recent Articles
1.
Canto-Santos J, Valls-Roca L, Tobias E, Garcia-Garcia F, Guitart-Mampel M, Andujar-Sanchez F, et al.
Acta Neuropathol Commun . 2025 Feb; 13(1):38. PMID: 39985015
Inclusion body myositis (IBM) is an inflammatory myopathy that displays proximal and distal muscle weakness. At the histopathological level, the muscles of IBM patients show inflammatory infiltrates, rimmed vacuoles and...
2.
Petazzi P, Gutierrez-Aguera F, Roca-Ho H, Castano J, Bueno C, Alvarez N, et al.
Front Cell Dev Biol . 2024 Dec; 12:1484955. PMID: 39676795
The CRISPR/Cas9 system has transformed genome editing by enabling precise modifications for diverse applications. Recent advancements, including base editing and prime editing, have expanded its utility beyond conventional gene knock-out...
3.
Alvarez N, Sevilla A
Int J Mol Sci . 2024 Jan; 25(2). PMID: 38256096
Photodynamic therapy (PDT) is a two-stage treatment that implies the use of light energy, oxygen, and light-activated compounds (photosensitizers) to elicit cancerous and precancerous cell death after light activation (phototoxicity)....
4.
Pedrosa L, Bedia C, Diao D, Mosteiro A, Ferres A, Stanzani E, et al.
Cells . 2023 May; 12(8). PMID: 37190034
Background: The high recurrence of glioblastoma (GB) that occurs adjacent to the resection cavity within two years of diagnosis urges an improvement of therapies oriented to GB local control. Photodynamic...
5.
Petazzi P, Miquel-Serra L, Huertas S, Gonzalez C, Boto N, Muniz-Diaz E, et al.
Clin Transl Med . 2022 Oct; 12(10):e1063. PMID: 36281739
The limited availability of red cells with extremely rare blood group phenotypes is one of the global challenges in transfusion medicine that has prompted the search for alternative self-renewable pluripotent...
6.
Gonzalez-Fernandez V, Sevilla A
Cells . 2022 Sep; 11(17). PMID: 36078122
IPSC-based disease modelling and pluripotency studies have sparked widespread enthusiasm for more than 16 years of research [...].
7.
Mazloom A, Xu H, Reig-Palou J, Vasileva A, Roman A, Mulero-Navarro S, et al.
Front Cell Dev Biol . 2022 Jun; 10:820255. PMID: 35652095
Characterization of pluripotent states, in which cells can both self-renew or differentiate, with the irreversible loss of pluripotency, are important research areas in developmental biology. Although microRNAs (miRNAs) have been...
8.
Sevilla E, Sevilla A
Sci Context . 2022 Jan; 33(4):423-440. PMID: 35086592
This article examines the medical and political discussions regarding a controversial medicinal bark from Ecuador - cundurango - that was actively sponsored by the Ecuadorian government as a new botanical...
9.
Sevilla A, Papatsenko D, Mazloom A, Xu H, Vasileva A, Unwin R, et al.
Front Cell Dev Biol . 2021 Apr; 9:630067. PMID: 33816475
Cell fate decisions during development are governed by multi-factorial regulatory mechanisms including chromatin remodeling, DNA methylation, binding of transcription factors to specific loci, RNA transcription and protein synthesis. However, the...
10.
Petazzi P, Menendez P, Sevilla A
Methods Mol Biol . 2020 Nov; 2454:559-574. PMID: 33190185
The realization of the full potential of human pluripotent stem cells (hPSCs), including human induced PSCs (iPSC), relies on the ability to precisely edit their genome in a locus-specific and...