Ana Barbas
Overview
Explore the profile of Ana Barbas including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
28
Citations
627
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ferreira I, Torrejon E, Abecasis B, Alexandre B, Gomes R, Verslype C, et al.
SLAS Discov
. 2024 Mar;
29(3):100154.
PMID: 38521503
Sorafenib is a multikinase inhibitor indicated for first-line treatment of unresectable hepatocellular carcinoma. Despite its widespread use in the clinic, the existing knowledge of sorafenib mode-of-action remains incomplete. To build...
2.
Silva G, Rodrigues A, Ferreira S, Matos C, Eleuterio R, Marques G, et al.
Biomolecules
. 2023 Mar;
13(3).
PMID: 36979394
The Notch signaling ligand JAG1 is overexpressed in various aggressive tumors and is associated with poor clinical prognosis. Hence, therapies targeting oncogenic JAG1 hold great potential for the treatment of...
3.
Moita M, Silva M, Diniz C, Serra M, Hoet R, Barbas A, et al.
Front Cardiovasc Med
. 2022 Dec;
9:1015473.
PMID: 36531712
Background: Activated cardiac fibroblasts (CF) play a central role in cardiac fibrosis, a condition associated with most cardiovascular diseases. Conversion of quiescent into activated CF sustains heart integrity upon injury....
4.
Silva G, Sales-Dias J, Casal D, Alves S, Domenici G, Barreto C, et al.
Cancers (Basel)
. 2021 Aug;
13(16).
PMID: 34439228
The Notch-signaling ligand DLL1 has emerged as an important player and promising therapeutic target in breast cancer (BC). DLL1-induced Notch activation promotes tumor cell proliferation, survival, migration, angiogenesis and BC...
5.
Sales-Dias J, Ferreira A, Lamy M, Domenici G, Monteiro S, Pires A, et al.
N Biotechnol
. 2021 May;
64:17-26.
PMID: 33992842
Notch signalling is a well-established oncogenic pathway, and its ligand Delta-like 1 (DLL1) is overexpressed in estrogen receptor-positive (ER) breast cancers and associated with poor patient prognosis. Hence, DLL1 has...
6.
Pinto C, Silva G, Ribeiro A, Oliveira M, Garrido M, Bandeira V, et al.
J Biotechnol
. 2019 Jun;
300:70-77.
PMID: 31150679
Adeno-associated viral vectors (AAV) for gene therapy applications are gaining momentum, with more therapies moving into later stages of clinical development and towards market approval, namely for cancer therapy. The...
7.
Sales-Dias J, Silva G, Lamy M, Ferreira A, Barbas A
PLoS One
. 2019 May;
14(5):e0217002.
PMID: 31107884
These findings provide further evidence that DLL1 exerts carcinogenic effects in BC cells. The dissimilar effects of DLL1 downregulation observed amongst MCF-7, BT474, and MDA-MB-231 cells is likely due to...
8.
Loureiro L, Sousa D, Ferreira D, Chai W, Lima L, Pereira C, et al.
Sci Rep
. 2018 Aug;
8(1):12196.
PMID: 30111774
Incomplete O-glycosylation is a feature associated with malignancy resulting in the expression of truncated glycans such as the sialyl-Tn (STn) antigen. Despite all the progress in the development of potential...
9.
Ferreira A, Lamy M, Margarida Rocha M, Silva G, Bandeiras T, Barbas A
Protein Expr Purif
. 2018 Jan;
146:8-16.
PMID: 29366964
Notch signalling is an evolutionary conserved cell-to-cell communication pathway crucial for development and tissue homeostasis. Abnormal Notch signalling by mutations or deregulated expression of its receptors and/or ligands can lead...
10.
Lamy M, Ferreira A, Dias J, Braga S, Silva G, Barbas A
N Biotechnol
. 2017 Aug;
39(Pt B):215-221.
PMID: 28842360
Notch signalling is an evolutionarily highly conserved pathway that plays a crucial role during embryonic development and in tissue homeostasis maintenance during adult life. Abnormal Notch signalling has been implicated...