Alexis Hubaud
Overview
Explore the profile of Alexis Hubaud including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
695
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Recent Articles
1.
Diaz-Cuadros M, Miettinen T, Skinner O, Sheedy D, Diaz-Garcia C, Gapon S, et al.
Nature
. 2023 Mar;
616(7956):E4.
PMID: 36949206
No abstract available.
2.
Diaz-Cuadros M, Miettinen T, Skinner O, Sheedy D, Diaz-Garcia C, Gapon S, et al.
Nature
. 2023 Jan;
613(7944):550-557.
PMID: 36599986
Animals display substantial inter-species variation in the rate of embryonic development despite a broad conservation of the overall sequence of developmental events. Differences in biochemical reaction rates, including the rates...
3.
Hubaud A, Singh A
Trends Genet
. 2021 Apr;
37(7):603-605.
PMID: 33902937
Drug discovery is a complex process with high attrition rate: only about half of the compounds in advanced preclinical stages actually enter human trials. Key to these failures is our...
4.
Diaz-Cuadros M, Wagner D, Budjan C, Hubaud A, Tarazona O, Donelly S, et al.
Nature
. 2020 Jan;
580(7801):113-118.
PMID: 31915384
The segmental organization of the vertebral column is established early in embryogenesis, when pairs of somites are rhythmically produced by the presomitic mesoderm (PSM). The tempo of somite formation is...
5.
Singh A, Sosa M, Fang J, Shanmukhappa S, Hubaud A, Fawcett C, et al.
Cell Rep
. 2019 Sep;
28(11):2767-2776.e5.
PMID: 31509740
The hormone αKlotho regulates lifespan in mice, as knockouts die early of what appears to be accelerated aging due to hyperphosphatemia and soft tissue calcification. In contrast, the overexpression of...
6.
Chal J, Al Tanoury Z, Oginuma M, Moncuquet P, Gobert B, Miyanari A, et al.
Development
. 2018 Mar;
145(6).
PMID: 29555813
Body skeletal muscles derive from the paraxial mesoderm, which forms in the posterior region of the embryo. Using microarrays, we characterize novel mouse presomitic mesoderm (PSM) markers and show that,...
7.
Hubaud A, Regev I, Mahadevan L, Pourquie O
Cell
. 2017 Sep;
171(3):668-682.e11.
PMID: 28942924
The periodic segmentation of the vertebrate body axis into somites, and later vertebrae, relies on a genetic oscillator (the segmentation clock) driving the rhythmic activity of signaling pathways in the...
8.
Bardot P, Vincent S, Fournier M, Hubaud A, Joint M, Tora L, et al.
Development
. 2017 Sep;
144(20):3808-3818.
PMID: 28893950
During development, tightly regulated gene expression programs control cell fate and patterning. A key regulatory step in eukaryotic transcription is the assembly of the pre-initiation complex (PIC) at promoters. PIC...
9.
Hubaud A, Pourquie O
Nat Rev Mol Cell Biol
. 2014 Oct;
15(11):709-21.
PMID: 25335437
Segmentation of the paraxial mesoderm is a major event of vertebrate development that establishes the metameric patterning of the body axis. This process involves the periodic formation of sequential units,...
10.
Hubaud A, Pourquie O
Dev Cell
. 2013 Feb;
24(2):115-6.
PMID: 23369707
Two studies from Delaune et al. (2012) and Harima et al. (2012), published in Developmental Cell and Cell Reports, respectively, used elegant genetic and imaging techniques to shed new light...