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Ajeet Pratap Singh

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Articles 24
Citations 535
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Recent Articles
1.
Pokrajac N, Singh A
Proc Natl Acad Sci U S A . 2024 Aug; 121(33):e2412259121. PMID: 39102561
No abstract available.
2.
Hubaud A, Singh A
Trends Genet . 2021 Apr; 37(7):603-605. PMID: 33902937
Drug discovery is a complex process with high attrition rate: only about half of the compounds in advanced preclinical stages actually enter human trials. Key to these failures is our...
3.
Singh A, Sosa M, Fang J, Shanmukhappa S, Hubaud A, Fawcett C, et al.
Cell Rep . 2019 Sep; 28(11):2767-2776.e5. PMID: 31509740
The hormone αKlotho regulates lifespan in mice, as knockouts die early of what appears to be accelerated aging due to hyperphosphatemia and soft tissue calcification. In contrast, the overexpression of...
4.
Paswan S, Gautam A, Verma P, Rao C, Sidhu O, Singh A, et al.
J Pharmacopuncture . 2018 Aug; 20(2):93-99. PMID: 30087785
Objectives: s L. (family: Selaginaceae), is often used in traditional Indian systems of medicine for the prevention and cure of several disorders and for the treatment of patient with spermatorrhoea,...
5.
Fadeev A, Mendoza-Garcia P, Irion U, Guan J, Pfeifer K, Wiessner S, et al.
Proc Natl Acad Sci U S A . 2018 Jan; 115(4):E630-E638. PMID: 29317532
Mutations in anaplastic lymphoma kinase (ALK) are implicated in somatic and familial neuroblastoma, a pediatric tumor of neural crest-derived tissues. Recently, biochemical analyses have identified secreted small ALKAL proteins (FAM150,...
6.
Singh A, Das R, Rao G, Aggarwal A, Diegelmann S, Evers J, et al.
PLoS Genet . 2017 Nov; 13(11):e1007083. PMID: 29091719
[This corrects the article DOI: 10.1371/journal.pgen.1003452.].
7.
Singh A, Foley J, Tandon A, Phadke D, Kinyamu H, Archer T
Oncotarget . 2017 Sep; 8(33):54925-54938. PMID: 28903392
Lymphatic vasculature is an important part of the cardiovascular system with multiple functions, including regulation of the return of interstitial fluid (lymph) to the bloodstream, immune responses, and fat absorption....
8.
Nusslein-Volhard C, Singh A
Bioessays . 2017 Feb; 39(3). PMID: 28176337
Pigment cells in zebrafish - melanophores, iridophores, and xanthophores - originate from neural crest-derived stem cells associated with the dorsal root ganglia of the peripheral nervous system. Clonal analysis indicates...
9.
Mahalwar P, Singh A, Fadeev A, Nusslein-Volhard C, Irion U
Biol Open . 2016 Oct; 5(11):1680-1690. PMID: 27742608
The conspicuous striped coloration of zebrafish is produced by cell-cell interactions among three different types of chromatophores: black melanophores, orange/yellow xanthophores and silvery/blue iridophores. During color pattern formation xanthophores undergo...
10.
Singh A, Dinwiddie A, Mahalwar P, Schach U, Linker C, Irion U, et al.
Dev Cell . 2016 Jul; 38(3):316-30. PMID: 27453500
The neural crest is a transient, multipotent embryonic cell population in vertebrates giving rise to diverse cell types in adults via intermediate progenitors. The in vivo cell-fate potential and lineage...