Scott R Manalis
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Explore the profile of Scott R Manalis including associated specialties, affiliations and a list of published articles.
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88
Citations
3372
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Recent Articles
1.
Feng H, Katsikis G, Napier I, Du G, Lim J, Doyle J, et al.
Lab Chip
. 2024 Oct;
24(23):5225-5237.
PMID: 39474789
Egg (oocyte) vitrification is the dominant method for preserving fertility for women of reproductive age. However, the method is typically performed by hand, requiring precise (∼0.1 to 10 μL) and...
2.
Schubert M, Tang T, Goodchild-Michelman I, Ryon K, Henriksen J, Chavkin T, et al.
Appl Environ Microbiol
. 2024 Oct;
90(11):e0084124.
PMID: 39470214
Importance: Cyanobacteria provide a potential avenue for both biomanufacturing and combatting climate change via high-efficiency photosynthetic carbon sequestration. This study identifies novel photosynthetic organisms isolated from a unique geochemical environment...
3.
Destro F, Wu W, Srinivasan P, Joseph J, Bal V, Neufeld C, et al.
Biotechnol Adv
. 2024 Aug;
76:108433.
PMID: 39168354
Current processes for the production of recombinant adeno-associated virus (rAAV) are inadequate to meet the surging demand for rAAV-based gene therapies. This article reviews recent advances that hold the potential...
4.
Wu W, Lam A, Suarez K, Smith G, Duquette S, Yu J, et al.
bioRxiv
. 2024 Jul;
PMID: 39005340
All cells are subject to geometric constraints, including the surface area-to-volume (SA/V) ratio, which can limit nutrient uptake, maximum cell size, and cell shape changes. Like the SA/V ratio of...
5.
Miettinen T, Gomez A, Wu Y, Wu W, Usherwood T, Hwang Y, et al.
Sci Adv
. 2024 Jul;
10(27):eadn8356.
PMID: 38968348
Eukaryotic phytoplankton, also known as algae, form the basis of marine food webs and drive marine carbon sequestration. Algae must regulate their motility and gravitational sinking to balance access to...
6.
Winter P, Ramseier M, Navia A, Saksena S, Strouf H, Senhaji N, et al.
bioRxiv
. 2024 Jun;
PMID: 38915726
Efforts to cure BCR::ABL1 B cell acute lymphoblastic leukemia (Ph+ ALL) solely through inhibition of ABL1 kinase activity have thus far been insufficient despite the availability of tyrosine kinase inhibitors...
7.
Wu W, Ishamuddin S, Quinn T, Yerrum S, Zhang Y, Debaize L, et al.
bioRxiv
. 2024 May;
PMID: 38712225
Cell density, the ratio of cell mass to volume, is an indicator of molecular crowding and therefore a fundamental determinant of cell state and function. However, existing density measurements lack...
8.
Miller A, Rodriguez F, Langenbucher A, Lin L, Bray C, Duquette S, et al.
Commun Biol
. 2024 Apr;
7(1):483.
PMID: 38643279
Leukemias and their bone marrow microenvironments undergo dynamic changes over the course of disease. However, little is known about the circulation kinetics of leukemia cells, nor the impact of specific...
9.
Miller A, Langenbucher A, Rodriguez F, Lin L, Bray C, Duquette S, et al.
bioRxiv
. 2023 Sep;
PMID: 37732189
Leukemias and their bone marrow microenvironment are known to undergo dynamic changes over the course of disease. However, relatively little is known about the circulation kinetics of leukemia cells, nor...
10.
Roller B, Hellerschmied C, Wu Y, Miettinen T, Gomez A, Manalis S, et al.
mBio
. 2023 Sep;
14(5):e0158523.
PMID: 37671861
Microbiologists have watched clear liquid turn cloudy for over 100 years. While the cloudiness of a culture is proportional to its total biomass, growth rates from optical density measurements are...