Alexandre Dalet
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Explore the profile of Alexandre Dalet including associated specialties, affiliations and a list of published articles.
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11
Citations
574
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Recent Articles
1.
Perego J, Mendes A, Bourbon C, Camosseto V, Combes A, Liu H, et al.
Sci Signal
. 2018 Jan;
11(514).
PMID: 29363586
Endoplasmic reticulum (ER) stress triggers or amplifies inflammatory signals and cytokine production in immune cells. Upon the resolution of ER stress, the inducible phosphatase 1 cofactor GADD34 promotes the dephosphorylation...
2.
Dalet A, Arguello R, Combes A, Spinelli L, Jaeger S, Fallet M, et al.
EMBO J
. 2017 Jan;
36(6):761-782.
PMID: 28100675
In innate immune responses, induction of type-I interferons (IFNs) prevents virus spreading while viral replication is delayed by protein synthesis inhibition. We asked how cells perform these apparently contradictory activities....
3.
Dalet A, Gatti E, Pierre P
FEBS Lett
. 2015 May;
589(14):1539-45.
PMID: 25979169
Viral triggering of the innate immune response in infected cells aims at delaying viral replication and prevents tissue spreading. Viral replication is delayed by host protein synthesis inhibition and infected...
4.
Claudio N, Dalet A, Gatti E, Pierre P
EMBO J
. 2013 Apr;
32(9):1214-24.
PMID: 23584529
The innate immune cell network detects specific microbes and damages to cell integrity in order to coordinate and polarize the immune response against invading pathogens. In recent years, a cross-talk...
5.
Guillaume B, Stroobant V, Bousquet-Dubouch M, Colau D, Chapiro J, Parmentier N, et al.
J Immunol
. 2012 Aug;
189(7):3538-47.
PMID: 22925930
We recently described two proteasome subtypes that are intermediate between the standard proteasome and the immunoproteasome. They contain only one (β5i) or two (β1i and β5i) of the three inducible...
6.
Clavarino G, Claudio N, Couderc T, Dalet A, Judith D, Camosseto V, et al.
PLoS Pathog
. 2012 May;
8(5):e1002708.
PMID: 22615568
Nucleic acid sensing by cells is a key feature of antiviral responses, which generally result in type-I Interferon production and tissue protection. However, detection of double-stranded RNAs in virus-infected cells...
7.
Clavarino G, Claudio N, Dalet A, Terawaki S, Couderc T, Chasson L, et al.
Proc Natl Acad Sci U S A
. 2012 Feb;
109(8):3006-11.
PMID: 22315398
In response to inflammatory stimulation, dendritic cells (DCs) have a remarkable pattern of differentiation that exhibits specific mechanisms to control the immune response. Here we show that in response to...
8.
Dalet A, Robbins P, Stroobant V, Vigneron N, Li Y, El-Gamil M, et al.
Proc Natl Acad Sci U S A
. 2011 Jun;
108(29):E323-31.
PMID: 21670269
A variety of unconventional translational and posttranslational mechanisms contribute to the production of antigenic peptides, thereby increasing the diversity of the peptide repertoire presented by MHC class I molecules. Here,...
9.
Dalet A, Stroobant V, Vigneron N, Van den Eynde B
Eur J Immunol
. 2010 Dec;
41(1):39-46.
PMID: 21182075
Peptide splicing allows the production of antigenic peptides composed of two fragments initially non-contiguous in the parental protein. The proposed mechanism of splicing is a transpeptidation occurring within the proteasome....
10.
Dalet A, Vigneron N, Stroobant V, Hanada K, Van den Eynde B
J Immunol
. 2010 Feb;
184(6):3016-24.
PMID: 20154207
Peptide splicing is a newly described mode of production of antigenic peptides presented by MHC class I molecules, whereby two noncontiguous fragments of the parental protein are joined together after...