Philippe Pierre
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Explore the profile of Philippe Pierre including associated specialties, affiliations and a list of published articles.
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98
Citations
11648
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Recent Articles
1.
Ferreira B, Mazeda C, Dourado E, Simoes J, Prata A, Arguello R, et al.
Arthritis Res Ther
. 2025 Feb;
27(1):35.
PMID: 39972361
Background: Plasmacytoid dendritic cells (pDCs) play a key role in systemic sclerosis (SSc) pathophysiology. However, despite the recognised importance of metabolic reprogramming for pDC function, their metabolic profile in SSc...
2.
Ferreira B, Silva I, Mendes A, Leite-Pinheiro F, Paton A, Paton J, et al.
Cell Commun Signal
. 2025 Feb;
23(1):66.
PMID: 39920698
Background: Fibrosis remains a major complication in several chronic diseases, including systemic sclerosis (SSc). Plasmacytoid dendritic cells (pDCs) are innate immune cells that play a key role in the development...
3.
Borelli A, Santamaria J, Zamit C, Apert C, Chevallier J, Pierre P, et al.
Nat Commun
. 2024 Aug;
15(1):6976.
PMID: 39143070
Regulatory T cells (T) are critical players of immune tolerance that develop in the thymus via two distinct developmental pathways involving CD25Foxp3 and CD25Foxp3 precursors. However, the mechanisms regulating the...
4.
Li S, Ouyang X, Sun H, Jin J, Chen Y, Li L, et al.
Cell Discov
. 2024 May;
10(1):53.
PMID: 38763950
Peripheral CD8 T cell number is tightly controlled but the precise molecular mechanism regulating this process is still not fully understood. In this study, we found that epilepsy patients with...
5.
de Cevins C, Delage L, Batignes M, Riller Q, Luka M, Remaury A, et al.
Cell Rep Med
. 2023 Dec;
4(12):101333.
PMID: 38118407
Gain-of-function mutations in stimulator of interferon gene 1 (STING1) result in STING-associated vasculopathy with onset in infancy (SAVI), a severe autoinflammatory disease. Although elevated type I interferon (IFN) production is...
6.
Char R, Liu Z, Jacqueline C, Davieau M, Delgado M, Soufflet C, et al.
Nat Commun
. 2023 Jul;
14(1):4290.
PMID: 37463962
Endo-lysosomes transport along microtubules and clustering in the perinuclear area are two necessary steps for microbes to activate specialized phagocyte functions. We report that RUN and FYVE domain-containing protein 3...
7.
Adamik J, Munson P, Hartmann F, Combes A, Pierre P, Krummel M, et al.
Nat Commun
. 2022 Sep;
13(1):5184.
PMID: 36056019
Cellular metabolism underpins immune cell functionality, yet our understanding of metabolic influences in human dendritic cell biology and their ability to orchestrate immune responses is poorly developed. Here, we map...
8.
Valecka J, Camosseto V, McEwan D, Terawaki S, Liu Z, Strock E, et al.
R Soc Open Sci
. 2021 Jul;
8(7):202333.
PMID: 34295519
We report here that RUFY4, a newly characterized member of the 'RUN and FYVE domain-containing' family of proteins previously associated with autophagy enhancement, is highly expressed in alveolar macrophages (AM)....
9.
Choteau S, Wagner A, Pierre P, Spinelli L, Brun C
Database (Oxford)
. 2021 Jun;
2021.
PMID: 34156446
The development of high-throughput technologies revealed the existence of non-canonical short open reading frames (sORFs) on most eukaryotic ribonucleic acids. They are ubiquitous genetic elements conserved across species and suspected...
10.
Gracia-Maldonado G, Clark J, Burwinkel M, Greenslade B, Wunderlich M, Salomonis N, et al.
Haematologica
. 2021 Apr;
107(4):803-815.
PMID: 33910331
Although great advances have been made in understanding the pathobiology of mixed lineage leukemia-rearranged (MLL-r) leukemias, therapies for this leukemia have remained limited, and clinical outcomes remain bleak. In order...