Alexandra Riddell
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Explore the profile of Alexandra Riddell including associated specialties, affiliations and a list of published articles.
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10
Citations
131
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Recent Articles
1.
Riddell A, Flynn A, Bergugnat H, Dowsett L, Miller A
Clin Sci (Lond)
. 2024 Oct;
138(20):1305-1323.
PMID: 39391895
Symmetric dimethylarginine (SDMA) is a methylated derivative of arginine, generated by all cells as a by-product of cellular metabolism and eliminated via the kidney. For many years SDMA has been...
2.
Kaneko N, Loughrey C, Smith G, Matsuda R, Hasunuma T, Mark P, et al.
Br J Pharmacol
. 2024 May;
181(18):3401-3419.
PMID: 38773354
Background And Purpose: The ryanodine receptor 2 (RyR2) is present in both the heart and kidneys, and plays a crucial role in maintaining intracellular Ca homeostasis in cells in these...
3.
Martin T, MacDonald E, Bradley A, Watson H, Saxena P, Rog-Zielinska E, et al.
Cardiovasc Res
. 2023 Jul;
119(16):2663-2671.
PMID: 37433039
Aims: Myocardial infarction (MI) is a major cause of death worldwide. Effective treatments are required to improve recovery of cardiac function following MI, with the aim of improving patient outcomes...
4.
Reel P, Reel S, van Kralingen J, Langton K, Lang K, Erlic Z, et al.
EBioMedicine
. 2022 Sep;
84:104276.
PMID: 36179553
Background: Arterial hypertension is a major cardiovascular risk factor. Identification of secondary hypertension in its various forms is key to preventing and targeting treatment of cardiovascular complications. Simplified diagnostic tests...
5.
Gerganova G, Riddell A, Miller A
Pharmacol Ther
. 2022 Jun;
240:108220.
PMID: 35667516
CNS border-associated macrophages (BAMs) are a small population of specialised macrophages localised in the choroid plexus, meningeal and perivascular spaces. Until recently, the function of this elusive cell type was...
6.
MacKenzie S, Saunders H, van Kralingen J, Robertson S, Riddell A, Zennaro M, et al.
Cancers (Basel)
. 2021 Nov;
13(21).
PMID: 34771478
Primary aldosteronism (PA) is a common and highly treatable condition, usually resulting from adrenocortical tumorous growth or hyperplasia. PA is currently underdiagnosed owing to its complex and protracted diagnostic procedures....
7.
He W, McCarroll C, Nather K, Ford K, Mangion K, Riddell A, et al.
Cardiovasc Res
. 2021 Jun;
118(6):1535-1547.
PMID: 34132807
Aims: Identifying novel mediators of lethal myocardial reperfusion injury that can be targeted during primary percutaneous coronary intervention (PPCI) is key to limiting the progression of patients with ST-elevation myocardial...
8.
Riddell A, McBride M, Braun T, Nicklin S, Cameron E, Loughrey C, et al.
Cardiovasc Res
. 2020 Mar;
116(8):1410-1423.
PMID: 32154891
Runt-related transcription factor-1 (RUNX1), also known as acute myeloid leukaemia 1 protein (AML1), is a member of the core-binding factor family of transcription factors which modulate cell proliferation, differentiation, and...
9.
McArthur L, Riddell A, Chilton L, Smith G, Nicklin S
Heliyon
. 2020 Jan;
6(1):e03031.
PMID: 31909243
Connexin 43 expression (Cx43) is increased in cardiac fibroblasts (CFs) following myocardial infarction. Here, potential mediators responsible for increasing Cx43 expression and effects of differential CF phenotype on cardiac myocyte...
10.
McCarroll C, He W, Foote K, Bradley A, McGlynn K, Vidler F, et al.
Circulation
. 2017 Oct;
137(1):57-70.
PMID: 29030345
Background: Myocardial infarction (MI) is a leading cause of heart failure and death worldwide. Preservation of contractile function and protection against adverse changes in ventricular architecture (cardiac remodeling) are key...