Alexander Pertsemlidis
Overview
Explore the profile of Alexander Pertsemlidis including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
53
Citations
5262
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Harbut E, Makris Y, Pertsemlidis A, Bleris L
SLAS Discov
. 2024 Nov;
29(8):100194.
PMID: 39522879
No abstract available.
2.
Jaiswal A, Dutta A, Srinivasan G, Yuan Y, Zhou D, Shaheen M, et al.
Nucleic Acids Res
. 2023 Nov;
51(22):12224-12241.
PMID: 37953292
BRCA1-deficient cells have increased IRE1 RNase, which degrades multiple microRNAs. Reconstituting expression of one of these, miR-4638-5p, resulted in synthetic lethality in BRCA1-deficient cancer cells. We found that miR-4638-5p represses...
3.
Elzi D, Bauta W, Sanchez J, Das T, Mogare S, Zannes Fatland P, et al.
FASEB J
. 2021 Feb;
35(3):e21427.
PMID: 33629776
Porphyrins are used for cancer diagnostic and therapeutic applications, but the mechanism of how porphyrins accumulate in cancer cells remains elusive. Knowledge of how porphyrins enter cancer cells can aid...
4.
Kosti A, Barreiro R, Guardia G, Ostadrahimi S, Kokovay E, Pertsemlidis A, et al.
Cancers (Basel)
. 2021 Jan;
13(2).
PMID: 33466745
Tumor suppressor microRNAs (miRNAs) have been explored as agents to target cancer stem cells. Most strategies use a single miRNA mimic and present many disadvantages, such as the amount of...
5.
Moroney J, Vasudev A, Pertsemlidis A, Zan H, Casali P
Nat Commun
. 2020 Oct;
11(1):5435.
PMID: 33116135
Memory B cells (MBCs) are long-lived and produce high-affinity, generally, class-switched antibodies. Here, we use a multiparameter approach involving CD27 to segregate naïve B cells (NBC), IgD unswitched (unsw)MBCs and...
6.
Kosti A, Du L, Shivram H, Qiao M, Burns S, Garcia J, et al.
Mol Cancer Res
. 2019 Oct;
18(1):68-78.
PMID: 31624087
13--retinoic acid (RA) is typically used in postremission maintenance therapy in patients with neuroblastoma. However, side effects and recurrence are often observed. We investigated the use of miRNAs as a...
7.
Charan M, Dravid P, Cam M, Audino A, Gross A, Arnold M, et al.
Int J Cancer
. 2019 Oct;
146(11):3184-3195.
PMID: 31621900
Ewing sarcoma (EWS) is the second most common and aggressive type of metastatic bone tumor in adolescents and young adults. There is unmet medical need to develop and test novel...
8.
Yu X, Zhang Y, Wu B, Kurie J, Pertsemlidis A
Mol Ther Oncolytics
. 2019 Sep;
14:288-298.
PMID: 31508486
Chemoresistance and metastasis are the major reasons for non-small cell lung cancer (NSCLC) treatment failure and patient deaths. We and others have shown that miR-195 regulates the sensitivity of NSCLC...
9.
Li Y, Nowak C, Withers D, Pertsemlidis A, Bleris L
CRISPR J
. 2019 Apr;
1:286-293.
PMID: 31021219
Unraveling the properties of biological networks is central to understanding both normal and disease cellular phenotypes. Networks consist of functional elements (nodes) that form a variety of diverse connections (edges),...
10.
Zhao Z, Partridge V, Sousares M, Shelton S, Holland C, Pertsemlidis A, et al.
PLoS One
. 2018 Dec;
13(12):e0208777.
PMID: 30550571
microRNA-2110 (miR-2110) was previously identified as inducing neurite outgrowth in a neuroblastoma cell lines BE(2)-C, suggesting its differentiation-inducing and oncosuppressive function in neuroblastoma. In this study, we demonstrated that synthetic...