Alexander Pertsemlidis
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Explore the profile of Alexander Pertsemlidis including associated specialties, affiliations and a list of published articles.
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53
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5262
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Recent Articles
11.
Du L, Zhao Z, Suraokar M, Shelton S, Ma X, Hsiao T, et al.
Oncotarget
. 2018 Jul;
9(51):29601-29618.
PMID: 30038707
LMO1 encodes a protein containing a cysteine-rich LIM domain involved in protein-protein interactions. Recent studies have shown that LMO1 functions as an oncogene in several cancer types, including non-small cell...
12.
Yu X, Zhang Y, Ma X, Pertsemlidis A
Cancer Lett
. 2018 Apr;
427:85-93.
PMID: 29656007
Microtubule-targeting agents (MTAs) are widely used for the treatment of non-small cell lung cancer (NSCLC). The response rate is only ∼25%, mainly attributable to drug resistance. To identify determinants of...
13.
Yu X, Zhang Y, Cavazos D, Ma X, Zhao Z, Du L, et al.
Cell Death Dis
. 2018 Feb;
9(2):193.
PMID: 29416000
miR-195 has recently been reported to function as a tumor suppressor in various cancers, including non-small cell lung cancer (NSCLC). However, the mechanisms by which miR-195 represses the tumorigenesis of...
14.
Lin J, Zandi R, Shao R, Gu J, Ye Y, Wang J, et al.
Sci Rep
. 2017 Aug;
7(1):9029.
PMID: 28831115
Through a new hypothesis-driven and microRNA-pathway-based SNP (miR-SNP) association study we identified a novel miR-SNP (rs713065) in the 3'UTR region of FZD4 gene linked with decreased risk of death in...
15.
Zhao Z, Ma X, Shelton S, Sung D, Li M, Hernandez D, et al.
Oncotarget
. 2016 Oct;
7(48):79372-79387.
PMID: 27764804
MYCN amplification is the most common genetic alteration in neuroblastoma and plays a critical role in neuroblastoma tumorigenesis. MYCN regulates neuroblastoma cell differentiation, which is one of the mechanisms underlying...
16.
Henry S, Kidner R, Reisenauer M, Magedov I, Kiss R, Mathieu V, et al.
Eur J Med Chem
. 2016 May;
120:313-28.
PMID: 27218860
Plants of the Amaryllidaceae family produce a large variety of alkaloids and non-basic secondary metabolites, many of which are investigated for their promising anticancer activities. Of these, crinine-type alkaloids based...
17.
Liu L, Pertsemlidis A, Ding L, Story M, Steinberg M, Sebastiani P, et al.
Exp Biol Med (Maywood)
. 2016 Mar;
241(7):706-18.
PMID: 27022141
Sickle cell disease (SCD) is a group of inherited blood disorders that have in common a mutation in the sixth codon of the β-globin (HBB) gene on chromosome 11. However,...
18.
Zhao Z, Ma X, Sung D, Li M, Kosti A, Lin G, et al.
RNA Biol
. 2015 Mar;
12(5):538-54.
PMID: 25760387
microRNA-449a (miR-449a) has been identified to function as a tumor suppressor in several types of cancers. However, the role of miR-449a in neuroblastoma has not been intensively investigated. We recently...
19.
Masi M, Frolova L, Yu X, Mathieu V, Cimmino A, De Carvalho A, et al.
Fitoterapia
. 2015 Jan;
102:41-8.
PMID: 25598189
A new alkaloid, belonging to the pretazettine group of Amaryllidaceae alkaloids, was isolated from dried bulbs of Narcissus jonquilla quail and named jonquailine. Its structure, including the absolute configuration, was...
20.
Borkowski R, Du L, Zhao Z, McMillan E, Kosti A, Yang C, et al.
Cancer Res
. 2014 Dec;
75(4):666-75.
PMID: 25519225
Lung cancer is the leading cause of cancer-related fatalities. Recent success developing genotypically targeted therapies, with potency only in well-defined subpopulations of tumors, suggests a path to improving patient survival....