Alexander E Mayer
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Explore the profile of Alexander E Mayer including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
111
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Recent Articles
1.
Rodionov E, Pogorelko V, Lupanov V, Mayer P, Mayer A
Materials (Basel)
. 2023 Aug;
16(16).
PMID: 37629893
Current progress in numerical simulations and machine learning allows one to apply complex loading conditions for the identification of parameters in plasticity models. This possibility expands the spectrum of examined...
2.
Loza-Valdes A, Mayer A, Kassouf T, Trujillo-Viera J, Schmitz W, Dziaczkowski F, et al.
Life Sci Alliance
. 2021 Jun;
4(8).
PMID: 34145024
Members of the protein kinase D (PKD) family (PKD1, 2, and 3) integrate hormonal and nutritional inputs to regulate complex cellular metabolism. Despite the fact that a number of functions...
3.
Trujillo-Viera J, El-Merahbi R, Schmidt V, Karwen T, Loza-Valdes A, Strohmeyer A, et al.
EMBO Mol Med
. 2021 May;
13(5):e13548.
PMID: 33949105
Lipids are the most energy-dense components of the diet, and their overconsumption promotes obesity and diabetes. Dietary fat content has been linked to the lipid processing activity by the intestine...
4.
El-Merahbi R, Viera J, Valdes A, Kolczynska K, Reuter S, Loffler M, et al.
Genes Dev
. 2020 Mar;
34(7-8):495-510.
PMID: 32139423
Obesity-induced diabetes affects >400 million people worldwide. Uncontrolled lipolysis (free fatty acid release from adipocytes) can contribute to diabetes and obesity. To identify future therapeutic avenues targeting this pathway, we...
5.
Mayer A, Loffler M, Loza Valdes A, Schmitz W, El-Merahbi R, Viera J, et al.
Sci Signal
. 2019 Aug;
12(593).
PMID: 31387939
Hepatic activation of protein kinase C (PKC) isoforms by diacylglycerol (DAG) promotes insulin resistance and contributes to the development of type 2 diabetes (T2D). The closely related protein kinase D...
6.
Loffler M, Mayer A, Viera J, Valdes A, El-Merahbi R, Ade C, et al.
EMBO J
. 2018 Nov;
37(22).
PMID: 30389661
Nutrient overload in combination with decreased energy dissipation promotes obesity and diabetes. Obesity results in a hormonal imbalance, which among others activates G protein-coupled receptors utilizing diacylglycerol (DAG) as secondary...
7.
Cai K, El-Merahbi R, Loeffler M, Mayer A, Sumara G
Sci Rep
. 2017 Aug;
7(1):7191.
PMID: 28775290
Adipocytes play a central role in maintaining metabolic homeostasis in the body. Differentiation of adipocyte precursor cells requires the transcriptional activity of peroxisome proliferator-activated receptor-γ (Pparγ) and CCAAT/enhancer binding proteins...
8.
Popova O, Jenniskens P, Emelyanenko V, Kartashova A, Biryukov E, Khaibrakhmanov S, et al.
Science
. 2013 Nov;
342(6162):1069-73.
PMID: 24200813
The asteroid impact near the Russian city of Chelyabinsk on 15 February 2013 was the largest airburst on Earth since the 1908 Tunguska event, causing a natural disaster in an...