Alex P Farfel
Overview
Explore the profile of Alex P Farfel including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
5
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Recent Articles
1.
Sinha S, Callow B, Farfel A, Roy S, Chen S, Masotti M, et al.
J Clin Invest
. 2024 Oct;
134(24).
PMID: 39480488
Estrogen receptor-positive (ER+) breast cancer commonly disseminates to bone marrow, where interactions with mesenchymal stromal cells (MSCs) shape disease trajectory. We modeled these interactions with tumor-MSC co-cultures and used an...
2.
Sinha S, Callow B, Farfel A, Roy S, Chen S, Rajendran S, et al.
bioRxiv
. 2023 Mar;
PMID: 36993616
Estrogen receptor-positive (ER+) breast cancer commonly disseminates to bone marrow, where interactions with mesenchymal stromal cells (MSCs) shape disease trajectory. We modeled these interactions with tumor-MSC co-cultures and used an...
3.
Buschhaus J, Rajendran S, Chen S, Wharram B, Bevoor A, Cutter A, et al.
Mol Cancer Res
. 2023 Feb;
21(5):458-471.
PMID: 36735350
Implications: This study reveals how MSCs reprogram metabolism of ER+ breast cancer cells and point to MCT4 as potential therapeutic target to overcome resistance to antiestrogen drugs.