Alessandra Donadini
Overview
Explore the profile of Alessandra Donadini including associated specialties, affiliations and a list of published articles.
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12
Citations
156
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0
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Recent Articles
1.
Sociali G, Galeno L, Parenti M, Grozio A, Bauer I, Passalacqua M, et al.
Eur J Med Chem
. 2015 Aug;
102:530-9.
PMID: 26310895
The NAD(+)-dependent sirtuin SIRT6 is highly expressed in human breast, prostate, and skin cancer where it mediates resistance to cytotoxic agents and prevents differentiation. Thus, SIRT6 is an attractive target...
2.
Maffei M, Mongera S, Terpstra L, Donadini A, Voorham Q, Meijer G, et al.
Cytogenet Genome Res
. 2014 Oct;
144(1):9-14.
PMID: 25323042
DNA aneuploid sublines in sporadic colorectal cancers (CRCs) are quite frequent (about 85%) and likely the consequence of chromosomal instability and DNA copy number aberrations (CNAs). In order to gain...
3.
Donadini A, Rosano C, Felli L, Ponassi M
Curr Drug Targets
. 2013 Apr;
14(6):653-61.
PMID: 23547808
Sir2-like proteins (Sirtuins) are a class of enzymes conserved throughout the kingdoms of life. In fact, from Archaea to Mammals, these (class III) NAD+-dependent deacetylases catalyse the removal of the...
4.
Castagnola P, Malacarne D, Scaruffi P, Maffei M, Donadini A, Di Nallo E, et al.
BMC Cancer
. 2011 Oct;
11:445.
PMID: 21995418
Background: The mucosae of the oral cavity are different at the histological level but appear all equally exposed to common genotoxic agents. As a result of this exposure, changes in...
5.
Pentenero M, Donadini A, Di Nallo E, Maffei M, Marino R, Familiari U, et al.
J Oral Pathol Med
. 2011 Sep;
41(2):119-23.
PMID: 21950471
Objective: 'Field cancerization' is an accepted model for oral carcinogenesis. So far, genetically altered fields have been just reported in the presence of carcinomas. This study assessed the distant mirror...
6.
Pentenero M, Donadini A, Di Nallo E, Maffei M, Marino R, Familiari U, et al.
Cancer
. 2011 May;
117(22):5052-7.
PMID: 21590686
Background: Oral verrucous carcinomas (OVCs) are characterized by better prognosis than oral squamous cell carcinomas (OSCCs). Because chromosomal instability (CIN) in solid tumors is indicative of prognosis, this study investigated...
7.
Donadini A, Maffei M, Cavallero A, Pentenero M, Malacarne D, Di Nallo E, et al.
Cell Oncol
. 2010 May;
32(5-6):373-83.
PMID: 20448331
Oral potentially malignant lesions (OPMLs) with dysplasia and aneuploidy are thought to have a high risk of progression into oral squamous cell carcinomas (OSCCs). Non-dysplastic "oral distant fields" (ODFs), characterized...
8.
Monticone M, Biollo E, Maffei M, Donadini A, Romeo F, Storlazzi C, et al.
Mol Cancer
. 2008 Dec;
7:92.
PMID: 19087308
Background: KRAS and BRAF mutations appear of relevance in the genesis and progression of several solid tumor types but the co-occurrence and interaction of these mutations have not yet been...
9.
Nardini M, Svergun D, Konarev P, Spano S, Fasano M, Bracco C, et al.
Protein Sci
. 2006 Apr;
15(5):1042-50.
PMID: 16597837
C-terminal binding proteins (CtBPs) are moonlighting proteins involved in nuclear transcriptional corepression and in Golgi membrane tubule fission. Structural information on CtBPs is available for their substrate-binding domain, responsible for...
10.
Donadini A, Giacopelli F, Ravazzolo R, Gandin V, Marchisio P, Biffo S
FEBS Lett
. 2006 Mar;
580(8):1983-7.
PMID: 16530192
Eukaryotic initiation factor 6 (eIF6, alias p27BBP) is required for the biogenesis of 60S ribosomal subunits. eIF6 expression levels are tightly regulated in vivo, where they correlate with cellular growth....