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Martino Bolognesi

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Articles 233
Citations 4489
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Recent Articles
1.
Chiarugi S, Margheriti F, De Lorenzi V, Martino E, Margheritis E, Moscardini A, et al.
Cell Chem Biol . 2025 Feb; PMID: 39999832
Thiazide and thiazide-like diuretics are among the most efficacious and used drugs for the treatment of hypertension, edema, and major cardiovascular outcomes. Despite more then than six decades of clinical...
2.
Chaves-Sanjuan A, DAbrosca G, Russo V, van Erp B, Del Cont-Bernard A, Capelli R, et al.
Nucleic Acids Res . 2024 Nov; 52(22):13945-13963. PMID: 39588759
The transcriptional regulator MucR from Brucella species controls the expression of many genes, including those involved in virulence, by binding AT-rich DNA regions. MucR and its homologs belong to the...
3.
Costa S, Minucci A, Kumawat A, De Bonis M, Prontera G, Gelsomino M, et al.
Br J Haematol . 2024 Sep; 205(5):1985-1994. PMID: 39295190
G6PD deficiency results from mutations in the X-linked G6PD gene. More than 200 variants are associated with enzyme deficiency: each one of them may either cause predisposition to haemolytic anaemia...
4.
Schulte T, Chaves-Sanjuan A, Speranzini V, Sicking K, Milazzo M, Mazzini G, et al.
Nat Commun . 2024 Jul; 15(1):6359. PMID: 39069558
Systemic light chain (LC) amyloidosis (AL) is a disease where organs are damaged by an overload of a misfolded patient-specific antibody-derived LC, secreted by an abnormal B cell clone. The...
5.
Spizzichino S, Di Fonzo F, Marabelli C, Tramonti A, Chaves-Sanjuan A, Parroni A, et al.
Mol Cell . 2024 Jul; 84(14):2682-2697.e6. PMID: 38996576
RNA can directly control protein activity in a process called riboregulation; only a few mechanisms of riboregulation have been described in detail, none of which have been characterized on structural...
6.
Saponaro A, Krumbach J, Chaves-Sanjuan A, Sharifzadeh A, Porro A, Castelli R, et al.
Proc Natl Acad Sci U S A . 2024 Jun; 121(27):e2402259121. PMID: 38917012
HCN1-4 channels are the molecular determinants of the I/I current that crucially regulates cardiac and neuronal cell excitability. HCN dysfunctions lead to sinoatrial block (HCN4), epilepsy (HCN1), and chronic pain...
7.
Coletta M, Bolognesi M, Ascenzi P
J Inorg Biochem . 2023 Nov; 250:112423. PMID: 37953207
No abstract available.
8.
Grandi A, Tomasi M, Ullah I, Bertelli C, Vanzo T, Accordini S, et al.
Vaccines (Basel) . 2023 Oct; 11(10). PMID: 37896949
The vaccination campaign against SARS-CoV-2 relies on the world-wide availability of effective vaccines, with a potential need of 20 billion vaccine doses to fully vaccinate the world population. To reach...
9.
Ascenzi P, Bolognesi M, Guertin M, Moens L
J Inorg Biochem . 2023 Oct; :112396. PMID: 37838607
No abstract available.
10.
Puri S, Schulte T, Chaves-Sanjuan A, Mazzini G, Caminito S, Pappone C, et al.
J Mol Biol . 2023 Jul; 435(18):168215. PMID: 37516426
Immunoglobulin light chain amyloidosis (AL) is caused by the aberrant production of amyloidogenic light chains (LC) that accumulate as amyloid deposits in vital organs. Distinct LC sequences in each patient...