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Alejandro J Cagnoni

Explore the profile of Alejandro J Cagnoni including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Del Rio M, Radicioni M, Cutine A, Marino K, Mora-Montes H, Cagnoni A, et al.
Glycobiology . 2024 Aug; 34(9). PMID: 39088584
The limited availability of efficient treatments for Candida infections and the increased emergence of antifungal-resistant strains stimulates the search for new antifungal agents. We have previously isolated a sunflower mannose-binding...
2.
Quintana J, Massaro M, Cagnoni A, Nunez-Franco R, Delgado S, Jimenez-Oses G, et al.
J Biol Chem . 2024 Jul; 300(8):107577. PMID: 39019214
The dimeric architecture of tandem-repeat type galectins, such as galectin-4 (Gal-4), modulates their biological activities, although the underlying molecular mechanisms have remained elusive. Emerging evidence show that tandem-repeat galectins play...
3.
Cagnoni A, Massaro M, Cutine A, Gimeno A, Perez-Saez J, Manselle Cocco M, et al.
J Biol Chem . 2024 Jul; 300(8):107573. PMID: 39009340
Galectins (Gals), a family of multifunctional glycan-binding proteins, have been traditionally defined as β-galactoside binding lectins. However, certain members of this family have shown selective affinity toward specific glycan structures...
4.
Massaro M, Cagnoni A, Medrano F, Perez-Saez J, Abdullayev S, Belkhadem K, et al.
Bioorg Med Chem . 2023 Sep; 94:117480. PMID: 37774448
Galectins, a family of endogenous glycan-binding proteins, play crucial roles in a broad range of physiological and pathological processes. Galectin-1 (Gal-1), a proto-type member of this family, is overexpressed in...
5.
Marino K, Cagnoni A, Croci D, Rabinovich G
Nat Rev Drug Discov . 2023 Feb; 22(4):295-316. PMID: 36759557
Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a broad range of physiological and pathological processes. As a group, these proteins use both extracellular and...
6.
Bannoud N, Stupirski J, Cagnoni A, Hockl P, Perez Saez J, Garcia P, et al.
Proc Natl Acad Sci U S A . 2023 Jan; 120(3):e2214350120. PMID: 36634146
Blockade of vascular endothelial growth factor (VEGF) signaling with bevacizumab, a humanized anti-VEGF monoclonal antibody (mAb), or with receptor tyrosine kinase inhibitors, has improved progression-free survival and, in some indications,...
7.
Rubione J, Perez P, Czernikier A, Duette G, Pereyra Gerber F, Salido J, et al.
mBio . 2022 Aug; 13(4):e0061122. PMID: 35943163
Combined Antiretroviral therapy (cART) suppresses HIV replication but fails to eradicate the virus, which persists in a small pool of long-lived latently infected cells. Immune activation and residual inflammation during...
8.
Bannoud N, Garcia P, Gambarte-Tudela J, Sundblad V, Cagnoni A, Bach C, et al.
Methods Mol Biol . 2022 Mar; 2442:635-653. PMID: 35320550
Development of an aberrant vascular network is a hallmark of the multistep pathological process of tumor growth and metastasis. In response to hypoxia, several pro-angiogenic factors are synthesized to support...
9.
Manselle Cocco M, Veigas F, Bach C, Blidner A, Cagnoni A, DAlotto-Moreno T, et al.
Medicina (B Aires) . 2021 Oct; 81(5):683-687. PMID: 34633939
The rapid spread of the SARS-CoV-2, the causative agent of the emergent pandemic disease COVID-19, requires the urgent commitment of the immunology community to understand the adaptive immune response developed...
10.
Porciuncula-Gonzalez C, Cagnoni A, Fontana C, Marino K, Saenz-Mendez P, Giacomini C, et al.
Bioorg Med Chem . 2021 Jul; 44:116309. PMID: 34293617
Galectins, soluble lectins widely expressed intra- and extracellularly in different cell types, play major roles in deciphering the cellular glycocode. Galectin-1 (Gal-1), a prototype member of this family, presents a...