Jeroen L A Pennings
Overview
Explore the profile of Jeroen L A Pennings including associated specialties, affiliations and a list of published articles.
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Articles
157
Citations
1706
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Recent Articles
1.
Luijten M, van Benthem J, Morita T, Corvi R, Escobar P, Fujita Y, et al.
Environ Mol Mutagen
. 2024 Dec;
PMID: 39628086
In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all...
2.
Zhou Z, Pennings J, Sahlin U
Environ Toxicol Pharmacol
. 2024 Dec;
113():104597.
PMID: 39622398
The Adverse Outcome Pathways (AOPs) framework is pivotal in toxicology, but the, terminology describing Key Event Relationships (KERs) varies within AOP guidelines.This study examined the usage of causal, observational and...
3.
Lee S, Baxter L, Duran M, Morris S, Mosley I, Fuentes K, et al.
Hum Mol Genet
. 2024 Nov;
34(1):85-100.
PMID: 39533854
Trisomy of human chromosome 21 (T21) gives rise to Down syndrome (DS), the most frequent live-born autosomal aneuploidy. T21 triggers genome-wide transcriptomic alterations that result in multiple atypical phenotypes with...
4.
Vandebriel R, Hakkert B, Pennings J, Rossi L, Bichlmaier I, Bil W
Crit Rev Toxicol
. 2024 Jul;
54(7):476-484.
PMID: 39041360
The European Union (EU) Chemicals Strategy for Sustainability regards chemicals that affect the immune system among the most harmful ones. The Extended One-Generation Reproductive Toxicity study (EOGRTS; Organisation for Economic...
5.
Wassenaar P, Minnema J, Vriend J, Peijnenburg W, Pennings J, Kienhuis A
Regul Toxicol Pharmacol
. 2024 Feb;
148:105589.
PMID: 38403009
Risk assessment of chemicals is a time-consuming process and needs to be optimized to ensure all chemicals are timely evaluated and regulated. This transition could be stimulated by valuable applications...
6.
Bakker-t Hart I, Bakker F, Pennings J, Talhout R
Tob Prev Cessat
. 2024 Feb;
10.
PMID: 38344395
Introduction: The addition of cooling substances, such as menthol, might be attractive for youth to start smoking waterpipe by reducing the harshness of the smoke, thereby facilitating inhalation. These compounds...
7.
Pennings J, Hellmich I, Boesveldt S, Talhout R
Tob Induc Dis
. 2024 Jan;
22.
PMID: 38204732
Introduction: Part of the appeal of e-cigarettes lies in their available flavors. To achieve attractive flavors, e-liquids contain many different flavoring agents, which allow many flavoring combinations. To advance our...
8.
Pennings J, Pauwels C, Schenk E, Talhout R
Tob Induc Dis
. 2023 Jul;
21:91.
PMID: 37456608
Introduction: Cigarillos have been reported to provide an alternative to cigarettes with a characterizing flavor, which are banned in the European Union. Additionally, they are cheaper than cigarettes. To better...
9.
Pauwels C, Visser W, Pennings J, Baloe E, Hartendorp A, van Tiel L, et al.
Drug Alcohol Depend
. 2023 May;
248:109914.
PMID: 37245418
Background: In the US, nicotine salts (with protonated nicotine instead of free-based nicotine) have been reported to lower the harshness and bitterness of e-cigarette aerosols, making it easier to inhale...
10.
Veltman C, Pennings J, van de Water B, Luijten M
Chem Res Toxicol
. 2023 May;
36(6):805-817.
PMID: 37156502
Nongenotoxic (NGTX) carcinogens induce cancer via other mechanisms than direct DNA damage. A recognized mode of action for NGTX carcinogens is induction of oxidative stress, a state in which the...