Aart Verhoef
Overview
Explore the profile of Aart Verhoef including associated specialties, affiliations and a list of published articles.
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29
Citations
224
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Recent Articles
1.
Murray S, Verhoef A, Adak A, Sen D, Salzman R, Jaiswal P, et al.
Curr Opin Plant Biol
. 2025 Jan;
83:102684.
PMID: 39754892
Plant diseases constantly threaten crops and food systems, while global connectivity further increases the risks of spreading existing and exotic pathogens. Here, we first explore how an integrative approach involving...
2.
Dimopoulou M, Verhoef A, Pennings J, van Ravenzwaay B, Rietjens I, Piersma A
Toxicol Appl Pharmacol
. 2018 Jul;
355:287.
PMID: 29980297
No abstract available.
3.
Dimopoulou M, Verhoef A, Gomes C, van Dongen C, Rietjens I, Piersma A, et al.
Toxicol Lett
. 2018 Jan;
286:10-21.
PMID: 29337257
In the present study, we show the value of combining toxico-dynamic and -kinetic in vitro approaches for embryotoxicity testing of azoles. Both the whole embryo culture (WEC) and the embryonic...
4.
Dimopoulou M, Verhoef A, Pennings J, van Ravenzwaay B, Rietjens I, Piersma A
Toxicology
. 2017 Oct;
392:96-105.
PMID: 28970091
We evaluated the effect of six azoles on embryonic development in the rat whole embryo culture (WEC). Using the total morphological scoring system (TMS), we calculated the ID concentration (effective...
5.
Dimopoulou M, Verhoef A, Pennings J, van Ravenzwaay B, Rietjens I, Piersma A
Toxicol Appl Pharmacol
. 2017 Mar;
322:15-26.
PMID: 28263823
Differential gene expression analysis in the rat whole embryo culture (WEC) assay provides mechanistic insight into the embryotoxicity of test compounds. In our study, we hypothesized that comparative analysis of...
6.
Dimopoulou M, Verhoef A, van Ravenzwaay B, Rietjens I, Piersma A
Reprod Toxicol
. 2016 Apr;
64:77-85.
PMID: 27094377
Embryotoxic responses are critically dependent on the timing of exposure during embryo development. Here, we examined the time- dependent developmental effects in rat embryos exposed to flusilazole (FLU), and their...
7.
Tonk E, Verhoef A, Gremmer E, Van Loveren H, Piersma A
Regul Toxicol Pharmacol
. 2015 Apr;
72(2):379-85.
PMID: 25882306
The developmental immunotoxicity of 4-methyl anisole (4MA) was investigated in the rat. Four study designs were used, with either premating or post-weaning onset of exposure, continued to postnatal day 50,...
8.
Tonk E, Robinson J, Verhoef A, Theunissen P, Pennings J, Piersma A
Reprod Toxicol
. 2013 Jul;
41:57-66.
PMID: 23811354
Transcriptomic evaluations may improve toxicity prediction of in vitro-based developmental models. In this study, transcriptomics was used to identify VPA-induced gene expression changes in rat whole embryo culture (WEC). Furthermore,...
9.
Tonk E, Verhoef A, Gremmer E, Van Loveren H, Piersma A
Toxicology
. 2013 Apr;
309:91-9.
PMID: 23623904
The aim of the present study was to determine the sensitivity of the developing immune system to ethanol (EtOH) after exposure from postnatal day (PND) 10 onward. Adult Wistar dams...
10.
Luijten M, Singh A, Bastian C, Westerman A, Pisano M, Pennings J, et al.
PLoS One
. 2013 Feb;
8(2):e55603.
PMID: 23409006
Exposure to an imbalance of nutrients prior to conception and during critical developmental periods can have lasting consequences on physiological processes resulting in chronic diseases later in life. Developmental programming...