Albert Tsai
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Explore the profile of Albert Tsai including associated specialties, affiliations and a list of published articles.
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39
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1022
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Recent Articles
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Tsai A, Singer R, Crocker J
Mol Cell
. 2018 Apr;
70(2):195-196.
PMID: 29677489
Lim et al. (2018) use live imaging in Drosophila embryos to show that enhancers can drive transcription from promoters on another chromosome when they are in close proximity. In addition,...
14.
Tsai A, Muthusamy A, Rp Alves M, Lavis L, Singer R, Stern D, et al.
Elife
. 2017 Nov;
6.
PMID: 29095143
Transcription factors bind low-affinity DNA sequences for only short durations. It is not clear how brief, low-affinity interactions can drive efficient transcription. Here, we report that the transcription factor Ultrabithorax...
15.
Crocker J, Tsai A, Stern D
Cell Rep
. 2017 Jan;
18(1):287-296.
PMID: 28052257
Regions of genomic DNA called enhancers encode binding sites for transcription factor proteins. Binding of activators and repressors increase and reduce transcription, respectively, but it is not understood how combinations...
16.
Yoon Y, Wu B, Buxbaum A, Das S, Tsai A, English B, et al.
Proc Natl Acad Sci U S A
. 2016 Nov;
113(44):E6877-E6886.
PMID: 27791158
Localization of mRNA is required for protein synthesis to occur within discrete intracellular compartments. Neurons represent an ideal system for studying the precision of mRNA trafficking because of their polarized...
17.
Zhang Z, English B, Grimm J, Kazane S, Hu W, Tsai A, et al.
Genes Dev
. 2016 Nov;
30(18):2106-2118.
PMID: 27798851
Transcription of protein-encoding genes in eukaryotic cells requires the coordinated action of multiple general transcription factors (GTFs) and RNA polymerase II (Pol II). A "step-wise" preinitiation complex (PIC) assembly model...
18.
Navon S, Kornberg G, Chen J, Schwartzman T, Tsai A, Puglisi E, et al.
Proc Natl Acad Sci U S A
. 2016 Jun;
113(26):7166-70.
PMID: 27307442
Bioinformatic analysis of Escherichia coli proteomes revealed that all possible amino acid triplet sequences occur at their expected frequencies, with four exceptions. Two of the four underrepresented sequences (URSs) were...
19.
Tsai A, Puglisi J, Uemura S
Prog Mol Biol Transl Sci
. 2016 Mar;
139:1-43.
PMID: 26970189
In order to coordinate the complex biochemical and structural feat of converting triple-nucleotide codons into their corresponding amino acids, the ribosome must physically manipulate numerous macromolecules including the mRNA, tRNAs,...
20.
Cazares P, Santiago P, Moulton D, Moran S, Tsai A
Acad Psychiatry
. 2015 Jun;
39(4):393-7.
PMID: 26063679
Suicide is an event that is almost universally encountered by psychiatrists and psychiatry residents. Because psychiatric patients are at a higher risk for completing suicide than patients of other specialties,...