Alastair R Hawkins
Overview
Explore the profile of Alastair R Hawkins including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
51
Citations
618
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Stamp A, Owen P, El Omari K, Lockyer M, Lamb H, Charles I, et al.
Proteins
. 2011 May;
79(7):2352-7.
PMID: 21560168
No abstract available.
22.
Paz S, Tizon L, Otero J, Llamas-Saiz A, Fox G, van Raaij M, et al.
ChemMedChem
. 2011 Jan;
6(2):266-72.
PMID: 21275050
No abstract available.
23.
Peon A, Otero J, Tizon L, Prazeres V, Llamas-Saiz A, Fox G, et al.
ChemMedChem
. 2010 Sep;
5(10):1726-33.
PMID: 20815012
The binding mode of several substrate analogues, (2R)-2-benzyl-3-dehydroquinic acids 4, which are potent reversible competitive inhibitors of type II dehydroquinase (DHQ2), the third enzyme of the shikimic acid pathway, has...
24.
Stamp A, Owen P, El Omari K, Nichols C, Lockyer M, Lamb H, et al.
Protein Sci
. 2010 Jul;
19(10):1897-905.
PMID: 20669241
YcbL has been annotated as either a metallo-β-lactamase or glyoxalase II (GLX2), both members of the zinc metallohydrolase superfamily, that contains many enzymes with a diverse range of activities. Here,...
25.
Zhao X, Hume S, Johnson C, Thompson P, Huang J, Gray J, et al.
Protein Sci
. 2010 May;
19(7):1405-19.
PMID: 20506376
The role of specific cleavage of transcription repressor proteins by proteases and how this may be related to the emerging theme of dinucleotides as cellular signaling molecules is poorly characterized....
26.
Prazeres V, Tizon L, Otero J, Guardado-Calvo P, Llamas-Saiz A, van Raaij M, et al.
J Med Chem
. 2009 Nov;
53(1):191-200.
PMID: 19911771
The shikimic acid pathway is essential to many pathogens but absent in mammals. Enzymes in its pathway are therefore appropriate targets for the development of novel antibiotics. Dehydroquinase is the...
27.
Prazeres V, Castedo L, Lamb H, Hawkins A, Gonzalez-Bello C
ChemMedChem
. 2009 Oct;
4(12):1980-4.
PMID: 19856378
No abstract available.
28.
Lamb H, Stammers D, Hawkins A
Sci Signal
. 2008 Aug;
1(33):pe38.
PMID: 18714085
Differential binding of dinucleotides to key regulatory proteins can modulate their interactions with other proteins and, in some cases, can signal fluctuations in the cellular redox state, to produce changes...
29.
Kotaka M, Johnson C, Lamb H, Hawkins A, Ren J, Stammers D
J Mol Biol
. 2008 Jul;
381(2):373-82.
PMID: 18602114
Amongst the most common protein motifs in eukaryotes are zinc fingers (ZFs), which, although largely known as DNA binding modules, also can have additional important regulatory roles in forming protein:protein...
30.
Sanchez-Sixto C, Prazeres V, Castedo L, Suh S, Lamb H, Hawkins A, et al.
ChemMedChem
. 2008 Jan;
3(5):756-70.
PMID: 18200648
Several 3-heteroaryl analogs of the known dehydroquinase inhibitor (1R,4R,5R)-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid (4) were synthesized and tested as inhibitors of Helicobacter pylori type II dehydroquinase, the third enzyme of the shikimic acid...