Alan D Roberts
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Explore the profile of Alan D Roberts including associated specialties, affiliations and a list of published articles.
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29
Citations
1859
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Recent Articles
1.
Johnston-Peck A, DuChene J, Roberts A, Wei W, Herzing A
Ultramicroscopy
. 2016 Jul;
170:1-9.
PMID: 27469265
Beam damage caused by energetic electrons in the transmission electron microscope is a fundamental constraint limiting the collection of artifact-free information. Through understanding the influence of the electron beam, experimental...
2.
Johnston-Peck A, Winterstein J, Roberts A, DuChene J, Qian K, Sweeny B, et al.
Ultramicroscopy
. 2016 Jan;
162:52-60.
PMID: 26744830
Low-angle annular dark field (LAADF) scanning transmission electron microscopy (STEM) imaging is presented as a method that is sensitive to the oxidation state of cerium ions in CeO2 nanoparticles. This...
3.
CD4 T cells specific for a latency-associated γ-herpesvirus epitope are polyfunctional and cytotoxic
Freeman M, Burkum C, Cookenham T, Roberts A, Lanzer K, Huston G, et al.
J Immunol
. 2014 Nov;
193(12):5827-34.
PMID: 25378595
The oncogenic γ-herpesviruses EBV and Kaposi sarcoma-associated herpesvirus are ubiquitous human pathogens that establish lifelong latent infections maintained by intermittent viral reactivation and reinfection. Effector CD4 T cells are critical...
4.
Freeman M, Roberts A, Burkum C, Woodland D, Blackman M
J Virol
. 2014 May;
88(14):7862-9.
PMID: 24789784
CD8 and CD4 T cells are each critically important for immune control of murine gammaherpesvirus 68 (γHV68) infection. In immunocompetent mice, acute γHV68 infection results in lifelong latency, but in...
5.
Connor L, Kohlmeier J, Ryan L, Roberts A, Cookenham T, Quinn A, et al.
Immun Ageing
. 2013 Nov;
10(1):40.
PMID: 24228632
No abstract available.
6.
Brincks E, Roberts A, Cookenham T, Sell S, Kohlmeier J, Blackman M, et al.
J Immunol
. 2013 Mar;
190(7):3438-46.
PMID: 23467933
Regulatory CD4(+)Foxp3(+) T cells (Tregs) are key regulators of inflammatory responses and control the magnitude of cellular immune responses to viral infections. However, little is known about how Tregs contribute...
7.
Freeman M, Burkum C, Lanzer K, Roberts A, Pinkevych M, Itakura A, et al.
J Autoimmun
. 2012 Dec;
42:71-9.
PMID: 23245703
Human herpesviruses establish lifelong latency. Viral recrudescence can lead to the development of cancers, immunoproliferative disorders, transplantation complications, and thrombocytopenia. Although platelet-specific autoantibodies have been reported in patients infected with...
8.
Connor L, Kohlmeier J, Ryan L, Roberts A, Cookenham T, Blackman M, et al.
Immun Ageing
. 2012 Dec;
9(1):28.
PMID: 23244347
Unlabelled: Background: Virus-specific memory CD8+ T cells persist long after infection is resolved and are important for mediating recall responses to secondary infection. Although the number of memory T cells...
9.
Kohlmeier J, Reiley W, Perona-Wright G, Freeman M, Yager E, Connor L, et al.
J Exp Med
. 2011 Jul;
208(8):1621-34.
PMID: 21788409
The development of T cell memory from naive precursors is influenced by molecular cues received during T cell activation and differentiation. In this study, we describe a novel role for...
10.
Kohlmeier J, Connor L, Roberts A, Cookenham T, Martin K, Woodland D
J Immunol
. 2010 Aug;
185(6):3456-62.
PMID: 20720204
Immune responsiveness declines with age in part due to the development of CD8(+) T cell clonal expansions (TCEs) that can dominate the peripheral T cell pool. Although some TCEs arise...