Alan D Roberts
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Explore the profile of Alan D Roberts including associated specialties, affiliations and a list of published articles.
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29
Citations
1859
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Recent Articles
11.
Kohlmeier J, Cookenham T, Roberts A, Miller S, Woodland D
Immunity
. 2010 Jul;
33(1):96-105.
PMID: 20637658
Memory CD8(+) T cells in the lung airways provide protection from secondary respiratory virus challenge by limiting early viral replication. Here, we demonstrate that although airway-resident memory CD8(+) T cells...
12.
Takamura S, Roberts A, Jelley-Gibbs D, Wittmer S, Kohlmeier J, Woodland D
J Exp Med
. 2010 May;
207(6):1153-60.
PMID: 20457758
After respiratory virus infections, memory CD8+ T cells are maintained in the lung airways by a process of continual recruitment. Previous studies have suggested that this process is controlled, at...
13.
Kohlmeier J, Cookenham T, Miller S, Roberts A, Christensen J, Thomsen A, et al.
J Immunol
. 2009 Sep;
183(7):4378-84.
PMID: 19734208
Effector T cells are a crucial component of the adaptive immune response to respiratory virus infections. Although it was previously reported that the chemokine receptors CCR5 and CXCR3 affect trafficking...
14.
Reiley W, Calayag M, Wittmer S, Huntington J, Pearl J, Fountain J, et al.
Proc Natl Acad Sci U S A
. 2008 Aug;
105(31):10961-6.
PMID: 18667699
CD4(+) T cell responses to aerosol Mycobacterium tuberculosis (Mtb) infection are characterized by the relatively delayed appearance of effector T cells in the lungs. This delay in the adaptive response...
15.
Kohlmeier J, Miller S, Smith J, Lu B, Gerard C, Cookenham T, et al.
Immunity
. 2008 Jul;
29(1):101-13.
PMID: 18617426
Innate recognition of invading pathogens in peripheral tissues results in the recruitment of circulating memory CD8(+) T cells to sites of localized inflammation during the early phase of a recall...
16.
Ely K, Ahmed M, Kohlmeier J, Roberts A, Wittmer S, Blackman M, et al.
J Immunol
. 2007 Sep;
179(6):3535-42.
PMID: 17785787
Increasing age is associated with the development of CD8+ T cell clonal expansions (TCE) that can dominate the peripheral T cell repertoire and interfere with immune responses to infection and...
17.
Hikono H, Kohlmeier J, Takamura S, Wittmer S, Roberts A, Woodland D
J Exp Med
. 2007 Jul;
204(7):1625-36.
PMID: 17606632
The contributions of different subsets of memory CD8+ T cells to recall responses at mucosal sites of infection are poorly understood. Here, we analyzed the CD8+ T cell recall responses...
18.
Powell T, Strutt T, Reome J, Hollenbaugh J, Roberts A, Woodland D, et al.
J Immunol
. 2007 Jan;
178(2):1030-8.
PMID: 17202366
We show in this study several novel features of T cell-based heterosubtypic immunity against the influenza A virus in mice. First, T cell-mediated heterosubtypic protection against lethal challenge can be...
19.
Ely K, Roberts A, Kohlmeier J, Blackman M, Woodland D
Exp Gerontol
. 2007 Jan;
42(5):427-31.
PMID: 17197143
The capacity of the immune system to mediate effective immune responses to pathogens declines with age. In the case of immune responses to newly encountered antigens, several studies have demonstrated...
20.
Lawrence B, Roberts A, Neumiller J, Cundiff J, Woodland D
J Immunol
. 2006 Oct;
177(9):5819-28.
PMID: 17056506
The response of CD8+ T cells to influenza virus is very sensitive to modulation by aryl hydrocarbon receptor (AhR) agonists; however, the mechanism underlying AhR-mediated alterations in CD8+ T cell...