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Ai-Long Huang

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Articles 170
Citations 5027
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Recent Articles
21.
Zhang H, Shao L, Lin Z, Long Q, Yuan H, Cai L, et al.
Signal Transduct Target Ther . 2022 Aug; 7(1):261. PMID: 35915083
Apolipoprotein E (APOE) plays a pivotal role in lipid including cholesterol metabolism. The APOE ε4 (APOE4) allele is a major genetic risk factor for Alzheimer's and cardiovascular diseases. Although APOE...
22.
Peng P, Deng H, Li Z, Chen Y, Fang L, Hu J, et al.
J Med Virol . 2022 Jul; 94(12):5691-5701. PMID: 35906179
Immune responses elicited by viral infection or vaccination play key roles in the viral elimination and the prevention of reinfection, as well as the protection of healthy persons. As one...
23.
Wei X, Fan S, Wang Y, Li S, Long S, Gan C, et al.
iScience . 2022 Jun; 25(6):104416. PMID: 35663023
The core promoter (CP) of hepatitis B virus (HBV) is critical for HBV replication by controlling the transcription of pregenomic RNA (pgRNA). Host factors regulating the activity of the CP...
24.
Li J, Wang J, Zhang W, Tu Z, Cai X, Wang Y, et al.
Biosens Bioelectron . 2022 Apr; 209:114226. PMID: 35413624
Protein sensors based on allosteric enzymes responding to target binding with rapid changes in enzymatic activity are potential tools for homogeneous assays. However, a high signal-to-noise ratio (S/N) is difficult...
25.
Qin Y, Yu H, Yuan S, Yang Z, Ren F, Wang Q, et al.
Front Microbiol . 2022 Feb; 12:795388. PMID: 35140694
Hepatitis B virus (HBV) infection remains a major health problem worldwide. Sufficient maintenance of the HBV covalently closed circular DNA (cccDNA), which serves as a template for HBV transcription, is...
26.
Hu J, Peng P, Cao X, Wu K, Chen J, Wang K, et al.
Cell Mol Immunol . 2022 Jan; 19(2):293-295. PMID: 35017716
No abstract available.
27.
Hu J, Wei X, Xiang J, Peng P, Xu F, Wu K, et al.
Genes Dis . 2021 Dec; 9(5):1290-1300. PMID: 34877393
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The Spike protein that mediates coronavirus entry into host cells is a major target for COVID-19...
28.
Gan C, Cui J, Zhang W, Wang Y, Huang A, Hu J
Front Microbiol . 2021 Dec; 12:783040. PMID: 34858381
Recombinant DNA technology is a vital method in human hepatitis B virus (HBV), producing reporter viruses or vectors for gene transferring. Researchers have engineered several genes into the HBV genome...
29.
Zhou H, Li F, Cheng S, Xu Y, Deng H, Gu D, et al.
Hepatology . 2021 Oct; 75(4):847-865. PMID: 34626132
Background And Aims: The mechanism underlying HCC metastasis remains unclear, many oncogenes are known to regulate this process. However, the role of alternative splicing (AS) in pro-metastatic HCC is poorly...
30.
Zhang Z, Chen D, Liu Q, Gan C, Jiang L, Zhu K, et al.
Pediatr Pulmonol . 2021 Sep; 57(1):49-56. PMID: 34559474
Objective: Few studies have explored the clinical features in children infected with SARS-CoV-2 and other common respiratory viruses, including respiratory syncytial virus (RSV), Influenza virus (IV), and adenovirus (ADV). Herein,...