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Wei-Xian Chen

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Articles 68
Citations 1535
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Recent Articles
1.
Cheng S, Chen W, Deng H, He X, Zhang H, Tan M, et al.
Clin Mol Hepatol . 2025 Feb; PMID: 39905842
Background: Hepatitis B virus (HBV) hijacks host cell metabolism, especially host glutamine metabolism, to support its replication. Glutamate dehydrogenase 1 (GDH1), a mitochondrial enzyme crucial for glutamine metabolism, can interact...
2.
Wu J, Cheng T, Zhu B, Gao H, Zheng L, Chen W
Sci Rep . 2023 Oct; 13(1):18390. PMID: 37884650
Mounting evidence indicate that cuproptosis, a novel form of programmed cell death, contributes to cancer development and progression. However, a comprehensive analysis regarding the expressions, functions, and regulatory network of...
3.
Cheng T, Wu J, Zhu B, Gao H, Zheng L, Chen W
J Cancer Res Clin Oncol . 2023 Sep; 149(18):16779-16795. PMID: 37728703
Background: Breast cancer (BCa) is a major challenge for women's health worldwide. Ferroptosis is closely related to tumorigenesis and cancer progression. However, the prognostic value of ferroptosis-related genes in BCa...
4.
Zhan X, Wu R, Kong X, You Y, He K, Sun X, et al.
Cancer Commun (Lond) . 2022 Nov; 43(2):225-245. PMID: 36346061
Background: Neutrophil extracellular traps (NETs) are considered significant contributors to cancer progression, especially metastasis. However, it is still unclear whether NETs are involved in hepatitis B virus (HBV)-related hepatocarcinogenesis and...
5.
Wang D, Yang S, Chen W
Malawi Med J . 2022 Mar; 33(3):226-228. PMID: 35233281
Background: Metastasis from extramammary primary tumor to breast is extremely rare. Case Summary: A 59-year-old woman with 1-year history of rectal cancer presented with asymptomatic breast mass. At 16 months...
6.
Qin Y, Yu H, Yuan S, Yang Z, Ren F, Wang Q, et al.
Front Microbiol . 2022 Feb; 12:795388. PMID: 35140694
Hepatitis B virus (HBV) infection remains a major health problem worldwide. Sufficient maintenance of the HBV covalently closed circular DNA (cccDNA), which serves as a template for HBV transcription, is...
7.
Zhou H, Li F, Cheng S, Xu Y, Deng H, Gu D, et al.
Hepatology . 2021 Oct; 75(4):847-865. PMID: 34626132
Background And Aims: The mechanism underlying HCC metastasis remains unclear, many oncogenes are known to regulate this process. However, the role of alternative splicing (AS) in pro-metastatic HCC is poorly...
8.
Yu H, Cheng S, Ren F, Chen Y, Shi X, Wong V, et al.
Clin Sci (Lond) . 2021 Jun; 135(12):1505-1522. PMID: 34128977
Chronic hepatitis B virus (HBV) infection is a significant public health burden worldwide. HBV covalently closed circular DNA (cccDNA) organized as a minichromosome in nucleus is responsible for viral persistence...
9.
Chen W, Wang D, Zhu B, Zhu Y, Zheng L, Feng Z, et al.
Aging (Albany NY) . 2021 Mar; 13(7):10415-10430. PMID: 33752173
Exosome-mediated intercellular communication is considered to be an effective mode for malignant cells to transform biological behaviors in stromal cells. However, the mechanisms by which exosomes modulate macrophages within tumor...
10.
Chen S, Hu Q, Chen H, Zhang F, Duan L, Wang B, et al.
Dis Markers . 2020 Oct; 2020:2032056. PMID: 33101541
Substantial advance supports that CMTM2 serve as an important performer in physiological and pathological processes. However, very little is clear about the relationship between CMTM2 and HBV-related disorders. Here, for...