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Genes & Diseases

'Genes & Diseases' is a peer-reviewed journal that focuses on the latest advancements in the field of genetics and their implications for human health. It covers a wide range of topics, including genetic disorders, gene therapy, molecular genetics, and personalized medicine. With its interdisciplinary approach, the journal provides a platform for researchers, clinicians, and geneticists to share their findings and contribute to the understanding and management of genetic diseases.

Details
Abbr. Genes Dis
Start 2014
End Continuing
Frequency Bimonthly, 2021-
p-ISSN 2352-4820
e-ISSN 2352-3042
Country Netherlands
Language English
Metrics
h-index / Ranks: 6577 56
SJR / Ranks: 2086 1446
CiteScore / Ranks: 1970 8.60
JIF / Ranks: 896 6.8
Recent Articles
1.
Yan W, Xiang S, Feng J, Zu X
Genes Dis . 2025 Mar; 12(3):101341. PMID: 40083330
Breast cancer (BC) is the most common malignant tumor and the leading cause of cancer-related deaths among women worldwide. Great progress has been recently achieved in controlling breast cancer; however,...
2.
Hu Y, Du G, Li C, Wang R, Liu J, Wang Y, et al.
Genes Dis . 2025 Mar; 12(3):101321. PMID: 40083329
Hepatocyte proliferation is essential for recovering liver function after injury. In liver surgery, the mechanical stimulation induced by hemodynamic changes triggers vascular endothelial cells (VECs) to secrete large amounts of...
3.
Hu D, Zhang Z, Wang Y, Li S, Zhang J, Wu Z, et al.
Genes Dis . 2025 Mar; 12(3):101394. PMID: 40083328
Transcription factor E74 like ETS transcription factor 4 (ELF4), a member of the ETS family, is highly expressed in normal human hematopoietic tissue, ovary, placenta, colon, and certain pathological cell...
4.
Liu M, Zhuang X, Zhang H, Ji W, Yuan G
Genes Dis . 2025 Mar; 12(3):101326. PMID: 40083327
tRNA-derived small RNAs (tsRNAs) are non-coding small RNAs that are produced through the precise cleavage of tRNA molecules under specific conditions. tsRNA has multiple functions, including inhibiting translation, acting in...
5.
Ding S, Hao Y, Qi Y, Wei H, Zhang J, Li H
Genes Dis . 2025 Mar; 12(3):101442. PMID: 40083326
Endometrial carcinoma (EC) is a prevalent gynecological cancer, and its interaction with the immune system is pivotal in cancer progression. This comprehensive review explores the molecular mechanisms involved in the...
6.
Shen Y, Chen J, Li X
Genes Dis . 2025 Mar; 12(3):101374. PMID: 40083325
With the rapid advancements in second-generation gene sequencing technologies, a growing number of driver genes and associated therapeutic targets have been unveiled for lung adenocarcinoma (LUAD) and lung squamous cell...
7.
Li X, Zhang H, Yu F, Xie S, Wang T, Zhang R, et al.
Genes Dis . 2025 Mar; 12(3):101333. PMID: 40083324
Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome arising from lipid metabolic imbalance, with its prevalence increasing globally. In this study, we observed a significant up-regulation of interferon...
8.
Zou J, Du C, Liu S, Zhao P, Gao S, Chen B, et al.
Genes Dis . 2025 Mar; 12(3):101336. PMID: 40083323
Although bone morphogenetic protein 2 (BMP2) can induce chondrogenic differentiation of mesenchymal stem cells (MSCs), its induction of endochondral ossification limits the application of BMP2-based cartilage regeneration. Here, we clarified...
9.
Zheng M, Yang Z, Shi L, Zhao L, Liu K, Tang N
Genes Dis . 2025 Mar; 12(3):101509. PMID: 40083322
Exosomes, a type of extracellular vesicle, are commonly found in different body fluids and are rich in nucleic acids (circRNA, lncRNAs, miRNAs, mRNAs, tRNAs, .), proteins, and lipids. They are...
10.
Zhang L, Ji C, Li Z, Jiwa H, Xie Z, Luo X, et al.
Genes Dis . 2025 Mar; 12(3):101308. PMID: 40070367
Bone morphogenetic protein 9 (BMP9) has remarkable potential to induce the differentiation of mesenchymal stem cells (MSCs) towards the osteoblastic lineage. Additionally, research suggests that certain growth factors have the...