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Ai-Long Huang

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Articles 170
Citations 5027
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Recent Articles
11.
Zhou P, Chang W, Gong D, Xia J, Chen W, Huang L, et al.
Cell Metab . 2023 Oct; 35(11):1961-1975.e6. PMID: 37797623
Emerging studies have addressed the tumor-promoting role of fructose in different cancers. The effects and pathological mechanisms of high dietary fructose on hepatocellular carcinoma (HCC) remain unclear. Here, we examined...
12.
Liu Y, Chen X, Zhao Y, Wang X, Luo Y, Chen L, et al.
Cell Rep . 2023 Jul; 42(8):112852. PMID: 37481718
The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is a major mediator of inflammation following stimulation with >45 bp double-stranded DNA (dsDNA). Herein, we identify a class of...
13.
Hu J, Huang A
Microorganisms . 2023 Mar; 11(3). PMID: 36985174
Eradication of cccDNA is an ideal goal of chronic hepatitis B (CHB) therapy. Understanding the changes in the cccDNA pool during therapy provides a basis for developing CHB treatment strategies....
14.
Wang Z, Dai Z, Hu M, Liu J, Liang H, Shen M, et al.
Med Oncol . 2023 Feb; 40(3):96. PMID: 36792863
Tubulin γ-1 (TUBG1) is a highly conserved component of the centrosome and its deregulation is involved in the development of several types of cancer. However, the role of TUBG1 in...
15.
Zhou P, Chang W, Gong D, Huang L, Liu R, Liu Y, et al.
Oncogene . 2023 Jan; 42(10):725-736. PMID: 36604567
Aberrantly elevated O-GlcNAcylation level is commonly observed in human cancer patients, and has been proposed as a potential therapeutic target. Speckle-type POZ protein (SPOP), an important substrate adaptor of cullin3-RING...
16.
Zhou Y, Gu H, Tang Q, Li F, Zhu J, Ai T, et al.
Front Pediatr . 2022 Oct; 10:975628. PMID: 36275068
According to analyses of etiology, clinical features, diagnostic methods, and treatment strategies by summarizing a case of unexplained acute hepatitis recently experienced, we are aiming to provide some information to...
17.
Wang P, Yang X, Guo L, Wang Y, Zhang W, Sun Y, et al.
Front Microbiol . 2022 Sep; 13:920280. PMID: 36060770
One of the most desirable targets for HBV medications is the sodium taurocholate cotransporting polypeptide (NTCP), an entry receptor for the hepatitis B virus (HBV). N-myristoylated preS1 2-48 (Myrcludex B...
18.
Peng P, Hu J, Deng H, Liu B, Fang L, Wang K, et al.
Cell Mol Immunol . 2022 Aug; 19(12):1440. PMID: 36042353
No abstract available.
19.
Li J, Wang J, Gan C, Cai X, Wang Y, Long Q, et al.
J Biotechnol . 2022 Aug; 357:100-107. PMID: 35963591
Caspases are a family of evolutionary conserved cysteine proteases that play key roles in programmed cell death and inflammation. Among the methods for the detection of caspase activity, biosensors based...
20.
Fan J, Long Q, Ren J, Chen H, Li M, Cheng Z, et al.
Eur J Clin Microbiol Infect Dis . 2022 Aug; 41(9):1155-1163. PMID: 35927536
Coronavirus disease 2019 (COVID-19) is a global public health concern. The purpose of this study was to investigate the association between genetic variants and SARS-CoV-2 infection and the COVID-19 severity...