Adrien Guillot
Overview
Explore the profile of Adrien Guillot including associated specialties, affiliations and a list of published articles.
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Articles
52
Citations
1196
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Recent Articles
11.
Cai X, Yin G, Chen S, Tacke F, Guillot A, Liu H
Cancer Cell Int
. 2024 Jun;
24(1):215.
PMID: 38902716
Hepatocellular carcinoma (HCC) poses a significant clinical challenge, necessitating the integration of immunotherapeutic approaches. Palbociclib, a selective CDK4/6 inhibitor, has demonstrated promising efficacy in preclinical HCC models and is being...
12.
Kiefer M, Meng Y, Yang N, Vahrenbrink M, Wulff S, Li C, et al.
Am J Physiol Endocrinol Metab
. 2024 Jun;
327(2):E203-E216.
PMID: 38895981
Retinol saturase (RetSat) is an oxidoreductase involved in lipid metabolism and the cellular sensitivity to peroxides. RetSat is highly expressed in metabolic organs like the liver and adipose tissue and...
13.
Liu H, Yin G, Kohlhepp M, Schumacher F, Hundertmark J, Hassan M, et al.
Adv Sci (Weinh)
. 2024 Jun;
11(30):e2403516.
PMID: 38868948
Metabolic dysfunction-associated steatotic liver disease (MASLD) is hallmarked by hepatic steatosis, cell injury, inflammation, and fibrosis. This study elaborates on a multicellular biochip-based liver sinusoid model to mimic MASLD pathomechanisms...
14.
Gribben C, Galanakis V, Calderwood A, Williams E, Chazarra-Gil R, Larraz M, et al.
Nature
. 2024 May;
630(8015):166-173.
PMID: 38778114
For many adult human organs, tissue regeneration during chronic disease remains a controversial subject. Regenerative processes are easily observed in animal models, and their underlying mechanisms are becoming well characterized,...
15.
Gao J, Lan T, Kostallari E, Guo Y, Lai E, Guillot A, et al.
J Hepatol
. 2024 May;
81(3):543-561.
PMID: 38763358
The hepatic sinusoids are composed of liver sinusoidal endothelial cells (LSECs), which are surrounded by hepatic stellate cells (HSCs) and contain liver-resident macrophages called Kupffer cells, and other patrolling immune...
16.
Feng D, Hwang S, Guillot A, Wang Y, Guan Y, Chen C, et al.
Cell Mol Gastroenterol Hepatol
. 2024 May;
18(3):101352.
PMID: 38697358
Alcohol-associated hepatitis (AH) is an acute-on-chronic liver injury that occurs in patients with chronic alcohol-associated liver disease (ALD). Patients with severe AH have high short-term mortality and lack effective pharmacologic...
17.
Niemietz P, Peiseler M, Kohlhepp M, Horn P, Matchett K, Wang Y, et al.
Hepatology
. 2024 Jan;
80(5):1104-1119.
PMID: 38231043
Background And Aims: Acute liver failure (ALF) is a rare but life-threatening condition, and DILI, particularly acetaminophen toxicity, is the leading cause of ALF. Innate immune mechanisms further perpetuate liver...
18.
Wilken S, Thevathasan T, Kamali C, Guillot A, Ihlow J, Fehrenbach U, et al.
Clin J Gastroenterol
. 2023 Dec;
17(2):300-306.
PMID: 38133737
Simultaneous occurrence of benign hepatic lesions of different types is a sporadic phenomenon. To the best of our knowledge, we report the first clinical case of a syndrome with simultaneous...
19.
Peiseler M, David B, Zindel J, Surewaard B, Lee W, Heymann F, et al.
Science
. 2023 Sep;
381(6662):eabq5202.
PMID: 37676943
Kupffer cells (KCs) are localized in liver sinusoids but extend pseudopods to parenchymal cells to maintain their identity and serve as the body's central bacterial filter. Liver cirrhosis drastically alters...
20.
Lan T, Guillot A, Tacke F
Signal Transduct Target Ther
. 2023 Aug;
8(1):319.
PMID: 37620333
No abstract available.