Adrian W Zuercher
Overview
Explore the profile of Adrian W Zuercher including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
680
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Willis E, Gillespie E, Guse K, Zuercher A, Kasermann F, Ruitenberg M, et al.
Brain Behav Immun
. 2022 Dec;
109:37-50.
PMID: 36581304
Intravenous immunoglobulin (IVIG) is a promising immune-modulatory therapy for limiting harmful inflammation and associated secondary tissue loss in neurotrauma. Here, we show that IVIG therapy attenuates spatial learning and memory...
2.
Wymann S, Dai Y, Nair A, Cao H, Powers G, Schnell A, et al.
J Biol Chem
. 2020 Dec;
296:100200.
PMID: 33334893
Human complement receptor 1 (HuCR1) is a pivotal regulator of complement activity, acting on all three complement pathways as a membrane-bound receptor of C3b/C4b, C3/C5 convertase decay accelerator, and cofactor...
3.
Lewis B, Ville J, Blacquiere M, Cen S, Spirig R, Zuercher A, et al.
BMC Immunol
. 2019 Dec;
20(1):44.
PMID: 31801459
Background: High-dose intravenous immunoglobulin (IVIg), and more recently, subcutaneously-delivered Ig (SCIg), are used to treat a variety of autoimmune diseases; however, there are challenges associated with product production, availability, access...
4.
Crow A, Kapur R, Koernig S, Campbell I, Jen C, Mott P, et al.
Sci Transl Med
. 2019 Aug;
11(506).
PMID: 31434758
Treatment of autoimmune and inflammatory diseases typically involves immune suppression. In an opposite strategy, we show that administration of the highly inflammatory erythrocyte-specific antibody Ter119 into mice remodels the monocyte...
5.
Zuercher A, Spirig R, Morelli A, Rowe T, Kasermann F
Autoimmun Rev
. 2019 Aug;
18(10):102366.
PMID: 31404703
In recent years, there has been a surge in the research and development of novel molecules as potential therapeutic alternatives to traditional treatments (such as intravenous immunoglobulins) for autoimmune disorders....
6.
Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates
Vonarburg C, Loetscher M, Spycher M, Kropf A, Illi M, Salmon S, et al.
Respir Res
. 2019 May;
20(1):99.
PMID: 31118031
Background: Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin serum levels. Interestingly, patients with Chronic Obstructive Pulmonary Disease or with...
7.
Koernig S, Campbell I, Mackenzie-Kludas C, Schaub A, Loetscher M, Ng W, et al.
Mucosal Immunol
. 2019 May;
12(4):1013-1024.
PMID: 31105268
Recurrent and persistent airway infections remain prevalent in patients with primary immunodeficiency (PID), despite restoration of serum immunoglobulin levels by intravenous or subcutaneous plasma-derived IgG. We investigated the effectiveness of...
8.
Spirig R, Campbell I, Koernig S, Chen C, Lewis B, Butcher R, et al.
J Immunol
. 2018 Mar;
200(8):2542-2553.
PMID: 29531170
Activation of Fc receptors and complement by immune complexes is a common important pathogenic trigger in many autoimmune diseases and so blockade of these innate immune pathways may be an...
9.
Zuercher A, Spirig R, Morelli A, Kasermann F
Autoimmun Rev
. 2016 Mar;
15(8):781-5.
PMID: 27019051
Polyclonal plasma-derived IgG is a mainstay therapeutic of immunodeficiency disorders as well as of various inflammatory autoimmune diseases. In immunodeficiency the primary function of IVIG/SCIG is to replace missing antibody...
10.
Rossato E, Ben Mkaddem S, Kanamaru Y, Hurtado-Nedelec M, Hayem G, Descatoire V, et al.
Arthritis Rheumatol
. 2015 Apr;
67(7):1766-77.
PMID: 25833812
Objective: Rheumatoid arthritis (RA), one of the most frequent chronic inflammatory rheumatic disorders, is characterized by the presence of autoantibodies and joint infiltration by activated immune cells, leading to cartilage...