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Adrian W R Serohijos

Explore the profile of Adrian W R Serohijos including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 883
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Recent Articles
1.
Erdogan A, Dasmeh P, Socha R, Chen J, Life B, Jun R, et al.
Nat Commun . 2024 Dec; 15(1):10813. PMID: 39737968
Heritable phenotypic variation plays a central role in evolution by conferring rapid adaptive capacity to populations. Mechanisms that can explain genetic diversity by describing connections between genotype and organismal fitness...
2.
Jasinska W, Dindo M, Cordoba S, Serohijos A, Laurino P, Brotman Y, et al.
Nat Commun . 2024 Jul; 15(1):6196. PMID: 39043701
No abstract available.
3.
Jasinska W, Dindo M, Cordoba S, Serohijos A, Laurino P, Brotman Y, et al.
Nat Commun . 2024 Jun; 15(1):5285. PMID: 38902266
Enzymes of the central metabolism tend to assemble into transient supramolecular complexes. However, the functional significance of the interactions, particularly between enzymes catalyzing non-consecutive reactions, remains unclear. Here, by co-localizing...
4.
Shaferman M, Gencel M, Alon N, Alasad K, Rotblat B, Serohijos A, et al.
Mol Biol Evol . 2023 May; 40(6). PMID: 37221009
The rampant variability in codon bias existing between bacterial genomes is expected to interfere with horizontal gene transfer (HGT), a phenomenon that drives bacterial adaptation. However, delineating the constraints imposed...
5.
NGuessan A, Brito I, Serohijos A, Shapiro B
Genome Biol Evol . 2021 Jun; 13(8). PMID: 34132784
Pangenomes-the cumulative set of genes encoded by a population or species-arise from the interplay of horizontal gene transfer, drift, and selection. The balance of these forces in shaping pangenomes has...
6.
Razban R, Dasmeh P, Serohijos A, Shakhnovich E
Biophys J . 2021 May; 120(12):2413-2424. PMID: 33932438
Every amino acid residue can influence a protein's overall stability, making stability highly susceptible to change throughout evolution. We consider the distribution of protein stabilities evolutionarily permittable under two previously...
7.
Jasinska W, Manhart M, Lerner J, Gauthier L, Serohijos A, Bershtein S
Nat Ecol Evol . 2020 Feb; 4(3):437-452. PMID: 32094541
Evolutionary dynamics in large asexual populations is strongly influenced by multiple competing beneficial lineages, most of which segregate at very low frequencies. However, technical barriers to tracking a large number...
8.
Gauthier L, Stynen B, Serohijos A, Michnick S
Bioessays . 2019 Dec; 42(2):e1900169. PMID: 31854021
How do common and rare genetic polymorphisms contribute to quantitative traits or disease risk and progression? Multiple human traits have been extensively characterized at the genomic level, revealing their complex...
9.
Mariani M, Dasmeh P, Fortin A, Caron E, Kalamujic M, Harrison A, et al.
Cells . 2019 Aug; 8(8). PMID: 31426476
Interferon (IFN) β and Tumor Necrosis Factor (TNF) are key players in immunity against viruses. Compelling evidence has shown that the antiviral and inflammatory transcriptional response induced by IFNβ is...
10.
Khoury S, Piltonen M, Ton A, Cole T, Samoshkin A, Smith S, et al.
Ann Neurol . 2019 Jun; 86(2):168-180. PMID: 31177555
Objective: Heightened somatic symptoms are reported by a wide range of patients with chronic pain and have been associated with emotional distress and physical dysfunction. Despite their clinical significance, molecular...