Adiljan Ibrahim
Overview
Explore the profile of Adiljan Ibrahim including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
1216
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sridhar S, Zhou Y, Ibrahim A, Bertazzo S, Wyss T, Swain A, et al.
Life Sci Alliance
. 2024 Oct;
8(1).
PMID: 39467636
Brain calcification, the ectopic mineral deposits of calcium phosphate, is a frequent radiological finding and a diagnostic criterion for primary familial brain calcification. We previously showed that microglia curtail the...
2.
Cignarella F, Filipello F, Bollman B, Cantoni C, Locca A, Mikesell R, et al.
Acta Neuropathol
. 2020 Aug;
140(4):513-534.
PMID: 32772264
Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) triggered by autoimmune mechanisms. Microglia are critical for the clearance of myelin debris in...
3.
Wang S, Mustafa M, Yuede C, Salazar S, Kong P, Long H, et al.
J Exp Med
. 2020 Jun;
217(9).
PMID: 32579671
TREM2 is a receptor for lipids expressed in microglia. The R47H variant of human TREM2 impairs ligand binding and increases Alzheimer's disease (AD) risk. In mouse models of amyloid β...
4.
Sun L, Mulinyawe S, Collins H, Ibrahim A, Li Q, Simon D, et al.
Cell
. 2018 Dec;
175(7):1811-1826.e21.
PMID: 30503207
Nervous system function depends on proper myelination for insulation and critical trophic support for axons. Myelination is tightly regulated spatially and temporally, but how it is controlled molecularly remains largely...
5.
Harterink M, Esteves da Silva M, Will L, Turan J, Ibrahim A, Lang A, et al.
Nat Methods
. 2017 Apr;
14(5):479-482.
PMID: 28394337
The actin cytoskeleton is essential for many fundamental biological processes, but tools for directly manipulating actin dynamics are limited to cell-permeable drugs that preclude single-cell perturbations. Here we describe DeActs,...
6.
Zuchero J, Fu M, Sloan S, Ibrahim A, Olson A, Zaremba A, et al.
Dev Cell
. 2015 Jul;
34(2):152-67.
PMID: 26166300
Myelin is essential in vertebrates for the rapid propagation of action potentials, but the molecular mechanisms driving its formation remain largely unknown. Here we show that the initial stage of...
7.
Rafalski V, Ho P, Brett J, Ucar D, Dugas J, Pollina E, et al.
Nat Cell Biol
. 2013 May;
15(6):614-24.
PMID: 23644469
Oligodendrocytes-the myelin-forming cells of the central nervous system-can be regenerated during adulthood. In adults, new oligodendrocytes originate from oligodendrocyte progenitor cells (OPCs), but also from neural stem cells (NSCs). Although...
8.
Dugas J, Ibrahim A, Barres B
Mol Cell Neurosci
. 2012 Apr;
50(1):45-57.
PMID: 22472204
Hypothyroidism is a well-described cause of hypomyelination. In addition, thyroid hormone (T3) has recently been shown to enhance remyelination in various animal models of CNS demyelination. What are the ways...
9.
Swiss V, Nguyen T, Dugas J, Ibrahim A, Barres B, Androulakis I, et al.
PLoS One
. 2011 Apr;
6(4):e18088.
PMID: 21490970
Differentiation of oligodendrocyte progenitor cells (OPCs) into mature oligodendrocytes requires extensive changes in gene expression, which are partly mediated by post-translational modifications of nucleosomal histones. An essential modification for oligodendrocyte...
10.
Dugas J, Cuellar T, Scholze A, Ason B, Ibrahim A, Emery B, et al.
Neuron
. 2010 Mar;
65(5):597-611.
PMID: 20223197
To investigate the role of microRNAs in regulating oligodendrocyte (OL) differentiation and myelination, we utilized transgenic mice in which microRNA processing was disrupted in OL precursor cells (OPCs) and OLs...