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Achim Pfosser

Explore the profile of Achim Pfosser including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 403
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Recent Articles
1.
Stachel G, Trenkwalder T, Gotz F, El Aouni C, Muenchmeier N, Pfosser A, et al.
Stem Cells . 2013 Jun; 31(9):1795-805. PMID: 23744498
The facilitated recruitment of vascular progenitor cells (VPCs) to ischemic areas might be a therapeutic target for neovascularization and repair. However, efficient and directed attraction of VPCs remains a major...
2.
Kupatt C, Hinkel R, Pfosser A, El-Aouni C, Wuchrer A, Fritz A, et al.
J Am Coll Cardiol . 2010 Jul; 56(5):414-22. PMID: 20650363
Objectives: We set out to investigate the ability of cardiotropic adeno-associated viral vector (AAV2.9 = recombinant adeno-associated virus [rAAV]) to induce prolonged expression of vascular endothelial growth factor (VEGF)-A and...
3.
Pinkenburg O, Pfosser A, Hinkel R, Bottcher M, Dinges C, Lebherz C, et al.
Hum Gene Ther . 2010 Apr; 20(2):159-67. PMID: 20377367
Therapeutic neovascularization is a concept well validated in animal models, however, without clear-cut success in clinical studies. To achieve prolonged transgene expression, recombinant adeno-associated virus (rAAV) was used in a...
4.
Pfosser A, El-Aouni C, Pfisterer I, Dietz M, Globisch F, Stachel G, et al.
Stem Cells . 2009 Dec; 28(2):376-85. PMID: 20014279
Embryonal endothelial progenitor cells (eEPCs) are capable of inducing therapeutic angiogenesis in a chronic hind limb model. However, the proportion of eEPCs recruited to the ischemic tissue appears to be...
5.
Deutsch M, Thieme S, Hinterseer M, Johnson T, Pfosser A, Reichart B, et al.
Int J Cardiol . 2009 Jan; 141(1):e4-7. PMID: 19131134
We report on a rare case of combined unilateral atresia of the proximal right pulmonary artery (PA) and left patent ductus arteriosus (PDA). A 46 year-old female patient with known...
6.
Kupatt C, Horstkotte J, Vlastos G, Pfosser A, Lebherz C, Semisch M, et al.
FASEB J . 2005 Jul; 19(11):1576-8. PMID: 16009705
Clonal embryonic endothelial progenitor cells (eEPCs) isolated from embryonic day 7.5 mice home specifically to hypoxic areas in mouse tumor metastases but spare normal organs and do not form carcinomas....
7.
Pfosser A, Thalgott M, Buttner K, Brouet A, Feron O, Boekstegers P, et al.
Cardiovasc Res . 2005 Jan; 65(3):728-36. PMID: 15664400
Objective: Induction of angiogenesis has been reported subsequent to eNOS overexpression or activation, the latter involving Hsp90 as a chaperone protein. Here, we investigated the potential of regional Hsp90 overexpression...
8.
Lebherz C, von Degenfeld G, Karl A, Pfosser A, Raake P, Pachmayr F, et al.
Endothelium . 2003 Dec; 10(4-5):257-65. PMID: 14660086
Therapeutic induction of angiogenesis has been shown in experimental hindlimb ischemia. An alternative to targeting the ischemic hindlimb tissue via the severely stenosed or occluded artery consists in the intact...
9.
Koczulla R, von Degenfeld G, Kupatt C, Krotz F, Zahler S, Gloe T, et al.
J Clin Invest . 2003 Jun; 111(11):1665-72. PMID: 12782669
Antimicrobial peptides are effector molecules of the innate immune system and contribute to host defense and regulation of inflammation. The human cathelicidin antimicrobial peptide LL-37/hCAP-18 is expressed in leukocytes and...