Antonis K Hatzopoulos
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Explore the profile of Antonis K Hatzopoulos including associated specialties, affiliations and a list of published articles.
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73
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2938
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Recent Articles
1.
Frazer N, Kaas G, Firmin C, Gamazon E, Hatzopoulos A
eNeuro
. 2024 Sep;
11(10).
PMID: 39349059
The Bone Morphogenetic Protein (BMP) signaling pathway is vital in neural progenitor cell proliferation, specification, and differentiation. The BMP signaling antagonist Gremlin 2 (Grem2) is the most potent natural inhibitor...
2.
Saleem M, Aden L, Mutchler A, Basu C, Ertuglu L, Sheng Q, et al.
Circ Res
. 2024 Sep;
135(9):890-909.
PMID: 39263750
Background: Salt sensitivity of blood pressure (SSBP), characterized by acute changes in blood pressure with changes in dietary sodium intake, is an independent risk factor for cardiovascular disease and mortality...
3.
Basu C, Cannon P, Awgulewitsch C, Galindo C, Gamazon E, Hatzopoulos A
Sci Rep
. 2024 May;
14(1):9991.
PMID: 38693202
Endothelial cells (ECs) have essential roles in cardiac tissue repair after myocardial infarction (MI). To establish stage-specific and long-term effects of the ischemic injury on cardiac ECs, we analyzed their...
4.
Bosma K, Ghosh M, Andrei S, Zhong L, Dunn J, Ricciardi V, et al.
Physiol Rep
. 2022 Apr;
10(7):e15212.
PMID: 35403369
Type 2 diabetes (T2D) affects >30 million Americans and nearly 70% of individuals with T2D will die from cardiovascular disease (CVD). Circulating levels of the inflammatory signaling lipid, prostaglandin E...
5.
Caleb Snider J, Riley L, Mallory N, Bersi M, Umbarkar P, Gautam R, et al.
Circulation
. 2021 Jan;
143(13):1317-1330.
PMID: 33474971
Background: Myocardial infarction (MI) induces an intense injury response that ultimately generates a collagen-dominated scar. Although required to prevent ventricular rupture, the fibrotic process is often sustained in a manner...
6.
Summers M, Richmond B, Kropski J, Majka S, Bastarache J, Hatzopoulos A, et al.
Am J Physiol Cell Physiol
. 2020 Oct;
320(1):C119-C131.
PMID: 33085496
The well-described Wnt inhibitor Dickkopf-1 (DKK1) plays a role in angiogenesis as well as in regulation of growth factor signaling cascades in pulmonary remodeling associated with chronic lung diseases (CLDs)...
7.
The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy
Raucci Jr F, Singh A, Soslow J, Markham L, Zhong L, Aljafar W, et al.
Int J Mol Sci
. 2020 Oct;
21(20).
PMID: 33050457
Brain-derived neurotrophic factor (BDNF) is a neuronal growth and survival factor that harbors cardioprotective qualities that may attenuate dilated cardiomyopathy. In ~30% of the population, BDNF has a common, nonsynonymous...
8.
Schroer A, Bersi M, Clark C, Zhang Q, Sanders L, Hatzopoulos A, et al.
JCI Insight
. 2019 Sep;
4(18).
PMID: 31534054
Over one million Americans experience myocardial infarction (MI) annually, and the resulting scar and subsequent cardiac fibrosis gives rise to heart failure. A specialized cell-cell adhesion protein, cadherin-11 (CDH11), contributes...
9.
Hatzopoulos A
Dis Model Mech
. 2019 Aug;
12(8).
PMID: 31439575
In the decade since Disease Models & Mechanisms was launched, the emergence of Big Data as the main foundation of biological information is having a profound effect on how we...
10.
Wu D, Hatzopoulos A
Exp Biol Med (Maywood)
. 2019 Feb;
244(2):147-156.
PMID: 30732465
By compiling findings from recent studies, this review will garner novel insight on the dynamic and complex role of BMP signaling in diseases of inflammation, highlighting the specific roles played...