Abdu I Alayash
Overview
Explore the profile of Abdu I Alayash including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
113
Citations
2728
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Goel Y, Arellano M, Fouda R, Garcia N, Lomeli R, Kerr D, et al.
PNAS Nexus
. 2025 Feb;
4(2):pgaf053.
PMID: 40007577
Several comorbidities of sickle cell disease (SCD) originate from red blood cell (RBC) instability, chronic inflammation, and oxidative stress. Development of scalable, cost-effective therapeutics suitable for chronic administration to prevent,...
2.
Jana S, Alayash A
Antioxid Redox Signal
. 2025 Jan;
PMID: 39846399
The mitochondria play a key role in maintaining oxygen homeostasis under normal oxygen tension (normoxia) and during oxygen deprivation (hypoxia). This is a critical balancing act between the oxygen content...
3.
Jahr J, MacKinnon K, Baum V, Alayash A
Transfusion
. 2025 Jan;
65(2):386-396.
PMID: 39748550
No abstract available.
4.
Hicks W, Jana S, Kassa T, Prince R, Cabrales P, Friedman J, et al.
Sci Rep
. 2024 Dec;
14(1):31441.
PMID: 39733159
Blood storage lesion induces cytosolic and membrane changes driven in part by hemoglobin (Hb) oxidation reactions within red blood cells (RBCs). A novel gel formulation containing the antioxidant curcuminoids in...
5.
Kassa T, Jana S, Baek J, Alayash A
Front Physiol
. 2024 Sep;
15:1427094.
PMID: 39224206
Electrostatic binding of deoxyhemoglobin (Hb) to cytoplasmic domain of band 3 anion transport protein occurs as part of the glycolytic regulation in red blood cells (RBCs). Hb oxidation intermediates not...
6.
Hicks W, Jana S, Kassa T, Prince R, Cabrales P, Friedman J, et al.
Res Sq
. 2024 May;
PMID: 38766242
Blood storage lesion induces cytosolic and membrane changes driven in part by hemoglobin (Hb) oxidation reactions within red blood cells (RBCs). A novel gel formulation containing the antioxidant curcuminoids in...
7.
Jana S, Kassa T, Wood F, Hicks W, Alayash A
Front Physiol
. 2023 Nov;
14:1278763.
PMID: 37916221
Red blood cells (RBCs) undergo metabolic, oxidative, and physiological changes during storage, collectively described as the "storage lesion." The impact of storage on oxygen homeostasis, following transfusion, is not fully...
8.
Jana S, Heaven M, Dahiya N, Stewart C, Anderson J, MacGregor S, et al.
J Photochem Photobiol B
. 2023 Mar;
241:112672.
PMID: 36871490
Continued efforts to reduce the risk of transfusion-transmitted infections (TTIs) through blood and blood components led to the development of ultraviolet (UV) light irradiation technologies known as pathogen reduction technologies...
9.
Jana S, Heaven M, Stauft C, Wang T, Williams M, DAgnillo F, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614003
The mechanistic interplay between SARS-CoV-2 infection, inflammation, and oxygen homeostasis is not well defined. Here, we show that the hypoxia-inducible factor (HIF-1α) transcriptional pathway is activated, perhaps due to a...
10.
Alayash A
Front Med Technol
. 2022 Dec;
4:1068972.
PMID: 36518991
Oxygen reversibly binds to the redox active iron, a transition metal in human Hemoglobin (Hb), which subsequently undergoes oxidation in air. This process is akin to iron rusting in non-biological...