Aaron S Meyer
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Explore the profile of Aaron S Meyer including associated specialties, affiliations and a list of published articles.
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49
Citations
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Recent Articles
1.
Kojima H, Morinelli T, Wang Y, Chin J, Meyer A, Kao Y, et al.
Am J Transplant
. 2024 Dec;
PMID: 39736469
As important immune regulatory cells, whether innate lymphoid cells (ILCs) are involved in liver transplantation (LT) remains unclear. In a murine orthotopic LT model, we dissected roles of ILCs in...
2.
Abraham A, Tan Z, Shrestha P, Bozich E, Meyer A
PLoS Comput Biol
. 2024 Dec;
20(12):e1012663.
PMID: 39715286
Systems serology aims to broadly profile the antigen binding, Fc biophysical features, immune receptor engagement, and effector functions of antibodies. This experimental approach excels at identifying antibody functional features that...
3.
Orcutt-Jahns B, Lima Junior J, Lin E, Rockne R, Matache A, Branciamore S, et al.
NPJ Syst Biol Appl
. 2024 Oct;
10(1):118.
PMID: 39389979
Cytokines operate in concert to maintain immune homeostasis and coordinate immune responses. In cases of ER breast cancer, peripheral immune cells exhibit altered responses to several cytokines, and these alterations...
4.
Tan Z, Meyer A
Cell Syst
. 2024 Aug;
15(8):679-693.
PMID: 39173584
Recent biological studies have been revolutionized in scale and granularity by multiplex and high-throughput assays. Profiling cell responses across several experimental parameters, such as perturbations, time, and genetic contexts, leads...
5.
Ramirez A, Orcutt-Jahns B, Pascoe S, Abraham A, Remigio B, Thomas N, et al.
bioRxiv
. 2024 Aug;
PMID: 39131377
Effective tools for exploration and analysis are needed to extract insights from large-scale single-cell measurement data. However, current techniques for handling single-cell studies performed across experimental conditions (e.g., samples, perturbations,...
6.
Hung E, Hodzic E, Tan Z, Meyer A
bioRxiv
. 2024 Jul;
PMID: 39026852
Tensor factorization is a dimensionality reduction method applied to multidimensional arrays. These methods are useful for identifying patterns within a variety of biomedical datasets due to their ability to preserve...
7.
Chin J, Tan Z, Chan L, Ruffin F, Parmar R, Ahn R, et al.
PNAS Nexus
. 2024 May;
3(5):pgae185.
PMID: 38779114
Methicillin-resistant (MRSA) bacteremia is a common and life-threatening infection that imposes up to 30% mortality even when appropriate therapy is used. Despite in vitro efficacy determined by minimum inhibitory concentration...
8.
Orcutt-Jahns B, Lima Junior J, Rockne R, Matache A, Branciamore S, Hung E, et al.
bioRxiv
. 2023 Nov;
PMID: 37961682
Cytokines mediate cell-to-cell communication across the immune system and therefore are critical to immunosurveillance in cancer and other diseases. Several cytokines show dysregulated abundance or signaling responses in breast cancer,...
9.
Creixell M, Taylor S, Gerritsen J, Bae S, Jiang M, Augustin T, et al.
bioRxiv
. 2023 Nov;
PMID: 37961516
Receptor tyrosine kinase (RTK)-targeted therapies are often effective but invariably limited by drug resistance. A major mechanism of acquired resistance involves "bypass" switching to alternative pathways driven by non-targeted RTKs...
10.
Orcutt-Jahns B, Emmel P, Snyder E, Taylor S, Meyer A
Sci Signal
. 2023 Oct;
16(807):eadg0699.
PMID: 37847758
The cytokine interleukin-2 (IL-2) has the potential to treat autoimmune disease but is limited by its modest specificity toward immunosuppressive regulatory T (T) cells. IL-2 receptors consist of combinations of...