Aaron McKenna
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Explore the profile of Aaron McKenna including associated specialties, affiliations and a list of published articles.
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53
Citations
37824
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Recent Articles
1.
Abdullah L, Emiliani F, Vaidya C, Stuart H, Musial S, Kolling F, et al.
Immunity
. 2025 Feb;
58(3):601-615.e9.
PMID: 40020673
Generating balanced populations of CD8 effector and memory T cells is necessary for immediate and durable immunity to infections and cancer. Yet, a definitive understanding of how a diverse CD8...
2.
Baron C, Mitchell O, Avagyan S, Menard R, Yang S, Robertson A, et al.
bioRxiv
. 2024 Sep;
PMID: 39314385
Hematopoietic stem cells are regulated by endothelial and mesenchymal stromal cells in the marrow niche1-3. Leukemogenesis was long believed to be solely driven by genetic perturbations in hematopoietic cells but...
3.
Abdullah L, Emiliani F, Vaidya C, Stuart H, Kolling F, Ackerman M, et al.
bioRxiv
. 2024 Apr;
PMID: 38585810
Generating balanced populations of CD8 effector and memory T cells is necessary for immediate and durable immunity to infections and cancer. Yet, a definitive understanding of CD8 differentiation remains unclear....
4.
Ameer A, Cheng Y, Saleem F, Uzma , McKenna A, Richmond A, et al.
Front Microbiol
. 2023 Oct;
14:1197838.
PMID: 37779716
In recent years, there has been an unprecedented advancement in analytical approaches that contribute to the mechanistic understanding of microbial communities by explicitly incorporating ecology and studying their assembly. In...
5.
Nguyen E, Fard V, Kim B, Collins S, Galey M, Nelson B, et al.
G3 (Bethesda)
. 2023 Aug;
13(10).
PMID: 37552705
There is increasing interest in the African spiny mouse (Acomys cahirinus) as a model organism because of its ability for regeneration of tissue after injury in skin, muscle, and internal...
6.
Nguyen E, Fard V, Kim B, Collins S, Galey M, Nelson B, et al.
bioRxiv
. 2023 Apr;
PMID: 37066261
There is increasing interest in the African spiny mouse ( ) as a model organism because of its ability for regeneration of tissue after injury in skin, muscle, and internal...
7.
Feng J, Dewitt 3rd W, McKenna A, Simon N, Willis A, Matsen 4th F
Ann Appl Stat
. 2022 Aug;
15(1):343-362.
PMID: 35990087
CRISPR technology has enabled cell lineage tracing for complex multicellular organisms through insertion-deletion mutations of synthetic genomic barcodes during organismal development. To reconstruct the cell lineage tree from the mutated...
8.
Emiliani F, Hsu I, McKenna A
ACS Synth Biol
. 2022 Jun;
11(7):2238-2246.
PMID: 35695379
Recombinant DNA is a fundamental tool in biotechnology and medicine. These DNA sequences are often built, replicated, and delivered in the form of plasmids. Validation of these plasmid sequences is...
9.
Anderson D, Pauler F, McKenna A, Shendure J, Hippenmeyer S, Horwitz M
Cell Syst
. 2022 Apr;
13(6):438-453.e5.
PMID: 35452605
Mutations are acquired frequently, such that each cell's genome inscribes its history of cell divisions. Common genomic alterations involve loss of heterozygosity (LOH). LOH accumulates throughout the genome, offering large...
10.
Brewer C, Nelson B, Wakenight P, Collins S, Okamura D, Dong X, et al.
Dev Cell
. 2021 Oct;
56(19):2722-2740.e6.
PMID: 34610329
Spiny mice (Acomys cahirinus) are terrestrial mammals that evolved unique scar-free regenerative wound-healing properties. Myofibroblasts (MFs) are the major scar-forming cell type in skin. We found that following traumatic injury...