A Sofia F Oliveira
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Explore the profile of A Sofia F Oliveira including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
283
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Recent Articles
1.
Kamsri B, Kamsri P, Punkvang A, Chimprasit A, Saparpakorn P, Hannongbua S, et al.
Biochemistry
. 2024 May;
63(11):1493-1504.
PMID: 38742407
DNA gyrases catalyze negative supercoiling of DNA, are essential for bacterial DNA replication, transcription, and recombination, and are important antibacterial targets in multiple pathogens, including , which in 2021 caused...
2.
Castelli M, Magni A, Bonollo G, Pavoni S, Frigerio F, Oliveira A, et al.
Protein Sci
. 2023 Dec;
33(3):e4880.
PMID: 38145386
Molecular chaperones, a family of proteins of which Hsp90 and Hsp70 are integral members, form an essential machinery to maintain healthy proteomes by controlling the folding and activation of a...
3.
Castelli M, Marchetti F, Osuna S, Oliveira A, Mulholland A, Serapian S, et al.
J Am Chem Soc
. 2023 Dec;
146(1):901-919.
PMID: 38116743
Protein functions are dynamically regulated by allostery, which enables conformational communication even between faraway residues, and expresses itself in many forms, akin to different "languages": allosteric control pathways predominating in...
4.
Daniels D, Ferrer-Vicens I, Hawksworth J, Andrienko T, Finnie E, Bretherton N, et al.
Nat Commun
. 2023 Oct;
14(1):6260.
PMID: 37803026
β-thalassemia is a prevalent genetic disorder causing severe anemia due to defective erythropoiesis, with few treatment options. Studying the underlying molecular defects is impeded by paucity of suitable patient material....
5.
Hutchins G, Noble C, Bunzel H, Williams C, Dubiel P, Yadav S, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(31):e2306046120.
PMID: 37487099
The electron-conducting circuitry of life represents an as-yet untapped resource of exquisite, nanoscale biomolecular engineering. Here, we report the characterization and structure of a de novo diheme "maquette" protein, 4D2,...
6.
Freeman S, Oliveira A, Gallio A, Rosa A, Simitakou M, Arthur C, et al.
J Biol Chem
. 2023 Jul;
299(8):105014.
PMID: 37414149
The target for humoral immunity, SARS-CoV-2 spike glycoprotein, has become the focus of vaccine research and development. Previous work demonstrated that the N-terminal domain (NTD) of SARS-CoV-2 spike binds biliverdin-a...
7.
Chan H, Oliveira A, Schofield C, Mulholland A, Duarte F
JACS Au
. 2023 Jun;
3(6):1767-1774.
PMID: 37384148
The SARS-CoV-2 main protease (M) plays an essential role in the coronavirus lifecycle by catalyzing hydrolysis of the viral polyproteins at specific sites. M is the target of drugs, such...
8.
Oliveira A, Shoemark D, Davidson A, Berger I, Schaffitzel C, Mulholland A
J Mol Cell Biol
. 2023 Mar;
15(3).
PMID: 36990513
The SARS-CoV-2 spike protein contains a functionally important fatty acid (FA) binding site, which is also found in some other coronaviruses, e.g. SARS-CoV and MERS-CoV. The occupancy of the FA...
9.
Elseginy S, Oliveira A, Shoemark D, Sessions R
RSC Med Chem
. 2022 Sep;
13(8):929-943.
PMID: 36092142
Targeting the colchicine binding site of α/β tubulin microtubules can lead to suppression of microtubule dynamics, cell cycle arrest and apoptosis. Therefore, the development of microtubule (MT) inhibitors is considered...
10.
Allen W, Corey R, Watkins D, Oliveira A, Hards K, Cook G, et al.
Elife
. 2022 Apr;
11.
PMID: 35486093
Transport of proteins across and into membranes is a fundamental biological process with the vast majority being conducted by the ubiquitous Sec machinery. In bacteria, this is usually achieved when...